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O17.1 OCCUPATIONS AND INDUSTRIES AT HIGH RISK FOR PLEURAL MESOTHELIOMA: A FRENCH POPULATION BASED CASE–CONTROL STUDY (1998–2002)
P. Rolland1,2, C. Henocque2, S. Ducamp2, A. Gilg Soit Ilg1, S. Chamming’s3, G. Launoy4, F. Galateau4, P. Astoul5, J. C. Pairon3, E. Imbernon1, M. Goldberg1, P. Brochard2.1Institut de Veille Sanitaire, Saint-Maurice, France; 2Institut de Santé Publique, d’Epidémiologie et de Développement, Bordeaux, France; 3Institut Interuniversitaire de Médecine du Travail, Paris, France; 4Centre Hospitalier Universitaire, Caen, France; 5Hôpital Sainte-Marguerite, Marseille, France
Introduction: In industrialised countries such as France, asbestos has been widely used for decades, and occupational exposure to asbestos has been identified as the most important risk factor for pleural mesothelioma.
Objective: To identify which occupations and industries that are at high risk for pleural mesothelioma among men and women.
Methods: A population based case–control study was conducted between 1998 and 2002 in 19 French cancer registration areas included in the Mesothelioma National Surveillance Program. This report is based on 455 cases (80% of males) histologically confirmed and 704 controls (matched for sex, age, and area residence), aged 41–94 years. Occupational history was collected by trained interviewers with a standardised questionnaire. Conditional logistic regression was applied to calculate odds ratios (ORs) and 95% confidence intervals (CIs) for each occupation and industry according to national and international standard classifications, taking subjects never employed in each occupational group as the reference.
Results: Among men, statistically significant highest risks were observed for plumbers and pipe fitters, welders, sheet metal workers, structural steel workers, and machinery fitters and assemblers, and for the industries of shipbuilding and repair, asbestos products, structural metal products, fabricated machineries, railroad equipment, construction, and chemicals. Among women, we observed a statistically significant excess risk only for secretaries (OR 3.2, …