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Lung function decline in laboratory animal workers: the role of sensitisation and exposure
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  • Published on:
    Authors' Reply
    • Lützen Portengen, Institute for Risk Assessment Sciences (IRAS)
    • Other Contributors:
      • A Hollander, G Doekes, G de Meer, and D Heederik

    Dear Editor

    We would like to thank Dr Preece for his letter.[1]

    He raises the issue that loss of symptomatic workers during follow-up does not explain the absence of a decline in lung function in workers who worked with laboratory animals for more than 4 years, and concludes that lung function decline in short-term employed workers is not sustained. We think that this interpretation of our data is somewhat ove...

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    Conflict of Interest:
    None declared.
  • Published on:
    Lung function decline in laboratory animal workers

    Dear Editor

    In their recent paper Portengen et al.[1] have made an important contribution to our understanding of laboratory animal allergy. However, they have omitted to draw attention to an observation of clinical importance to occupational physicians.

    They have suggested that the lack of decline in lung function in "experienced" workers may be due to the healthy worker effect. Their suggestion...

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    Conflict of Interest:
    None declared.