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Occupational risk factors for symptomatic lumbar disc herniation; a case-control study
  1. A Seidler1,
  2. U Bolm-Audorff2,
  3. T Siol3,
  4. N Henkel1,
  5. C Fuchs1,
  6. H Schug1,
  7. F Leheta4,
  8. G Marquardt5,
  9. E Schmitt6,
  10. P T Ulrich7,
  11. W Beck8,
  12. A Missalla8,
  13. G Elsner1
  1. 1Institute of Occupational Medicine, Johann Wolfgang Goethe-University, Frankfurt/Main, Germany
  2. 2Social Ministry of Hesse, Occupational Health Division, Wiesbaden, Germany
  3. 3Institute for Psychosomatic Medicine and Psychotherapy, University of Köln, Germany
  4. 4Neurosurgical Clinic, Brüderkrankenhaus, Frankfurt/Main, Germany
  5. 5Neurosurgical Clinic, Johann Wolfgang Goethe University, Frankfurt/Main, Germany
  6. 6Orthopaedic Clinic Friedrichsheim, Johann Wolfgang Goethe University, Frankfurt/Main, Germany
  7. 7Neurosurgical Clinic Offenbach, Germany
  8. 8Orthopaedic Physician, Frankfurt/Main, Germany
  1. Correspondence to:
 Dr A Seidler
 Institut für Arbeitsmedizin, Johann Wolfgang Goethe-Universität, Theodor-Stern-Kai 7, D-60590 Frankfurt/Main, Germany; A.Seidler{at}


Background: Previous studies mostly did not separate between symptomatic disc herniation combined with osteochondrosis/spondylosis of the lumbar spine and symptomatic disc herniation in radiographically normal intervertebral spaces. This may at least in part explain the differences in the observed risk patterns.

Aims: To investigate the possible aetiological relevance of physical and psychosocial workload to lumbar disc herniation with and without concomitant osteochondrosis/spondylosis.

Methods: A total of 267 cases with acute lumbar disc herniation (in two practices and four clinics) and 197 control subjects were studied. Data were gathered in a structured personal interview and analysed using logistic regression to control for age, region, nationality, and diseases affecting the lumbar spine. Cases without knowledge about osteochondrosis/spondylosis (n=42) were excluded from analysis. Risk factors were examined separately for those cases with (n=131) and without (n=94) radiographically diagnosed concomitant osteochondrosis or spondylosis.

Results: There was a statistically significant positive association between extreme forward bending and lumbar disc herniation with, as well as without concomitant osteochondrosis/spondylosis. There was a statistically significant relation between cumulative exposure to weight lifting or carrying and lumbar disc herniation with, but not without, concomitant osteochondrosis/spondylosis. Cases with disc herniation reported time pressure at work as well as psychic strain through contact with clients more frequently than control subjects.

Conclusions: Further larger studies are needed to verify the concept of distinct aetiologies of lumbar disc herniation in relatively younger persons with otherwise normal discs and of disc herniation in relatively older persons with structurally damaged discs.

  • case-control study
  • lumbar disc herniation
  • risk factors
  • weight carrying/lifting
  • extreme forward bending
  • psychosocial workload
  • CI, confidence interval
  • CT, computed tomography
  • JEM, job exposure matrix
  • MRI, magnetic resonance imaging
  • OR, odds ratio

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