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Occupational asthma from fungicides fluazinam and chlorothalonil
  1. A Draper1,
  2. P Cullinan1,
  3. C Campbell2,
  4. M Jones1,
  5. A Newman Taylor1
  1. 1Department of Occupational & Environmental Medicine, Royal Brompton Hospital & NHLI, 1b Manresa Road, London SW3 6LR, UK
  2. 2Syngenta International AG, WRO 1007.1.37, Werk Rosental, Schwarzwaldallee 215, CH-4025 Basel, Switzerland
  1. Correspondence to:
 Dr A Draper, Chest Clinic, St George's Hospital, Blackshaw Road, Tooting, London SW17 0QT, UK;


We report two cases of occupational asthma caused by sensitisation to powdered fungicides fluazinam and chlorothalonil, from the same fungicide formulation plant. Both developed work related lower respiratory symptoms after a latent interval of asymptomatic exposure. The diagnosis in each case was confirmed with a serial peak flow record in the workplace followed by specific inhalation tests. These fungicides are known to cause dermatitis; this report indicates that these compounds can induce specific immunological reactions in the airways as well as skin.

  • occupational asthma
  • fungicide
  • fluazinam
  • chlorothalonil

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