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  1. L. Belin,
  2. A. Bouhuys,
  3. W. Hoekstra,
  4. M.-B. Johansson,
  5. S.-E. Lindell,
  6. J. Pool
  1. Departments of Allergology and Clinical Physiology, Sahlgrenska Sjukhuset, Gothenburg, Sweden
  2. The Laboratory of Clinical Physiology, University Hospital, Leiden, The Netherlands


    The prevalence of byssinosis and chronic respiratory symptoms was studied in 117 workers in four Swedish cotton mills. Changes of forced expiratory volume in 0·75 sec. (F.E.V.0·75) during a Monday and a Wednesday were assessed in 64 male workers in four cardrooms in these mills. Dust sampling was performed with weighed millipore filters.

    Prevalences of byssinosis as judged from the workers' histories were 68%, 55%, 44%, and 25% in the four mills; the lowest prevalence of 25% was found in a mill spinning both high grade cotton yarn and rayon. Among 67 workers in the mills having a byssinosis prevalence of 68% and 55%, 60% were non-smokers, 70% had chronic cough, and 27% had chronic dyspnoea. The F.E.V.0·75 decreased on Monday in workers who gave a history of Monday dyspnoea, and to a lesser degree, but still significantly, in those who did not.

    In spite of marked differences in fine dust (i.e., dust smaller than 2 mm. diameter) concentrations in the four cardrooms, no significant relations between dust content, byssinosis prevalence, and F.E.V.0·75 changes on Monday could be demonstrated.

    The prevention and treatment of byssinosis is discussed. Workers at risk should receive a periodical medical examination including at least a spirographical pulmonary function test at intervals of one year or less.

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    • Present address: John B. Pierce Foundation Laboratory, New Haven, Conn., U.S.A.

    • Present address: Department of Clinica Physiology, Malmö General Hospital, Malmö, Sweden.

    • * This investigation was supported by grants from the Swedish Medical Research Council and the National Tuberculosis Association—American Thoracic Society.