Assessment of primary, oxidative and excision repaired DNA damage in hospital personnel handling antineoplastic drugs

M Villarini, L Dominici, R Piccinini, C Fatigoni… - …, 2010 - academic.oup.com
Abstract The International Agency for Research on Cancer has classified several
antineoplastic drugs in Group 1 (human carcinogens), among which chlorambucil …

Micronuclei and chromosome aberrations in subjects occupationally exposed to antineoplastic drugs: a multicentric approach

M Moretti, MG Grollino, S Pavanello… - International archives of …, 2015 - Springer
Objectives Recently published works showed that occupational exposure to antineoplastic
drugs (ANPD) is still frequent in hospital settings, despite significant safety policy …

Evaluation of cytotoxicity, genotoxicity, and apoptosis of wastewater before and after disinfection with performic acid

P Ragazzo, D Feretti, S Monarca, L Dominici, E Ceretti… - Water research, 2017 - Elsevier
Disinfection with performic acid (PFA) represents an emerging technology in wastewater
treatment. Many recent studies indicate its effectiveness and suitability as a disinfectant for …

Antigenotoxic effect, composition and antioxidant activity of Dendrobium speciosum

M Moretti, L Cossignani, F Messina, L Dominici… - Food chemistry, 2013 - Elsevier
The chemical composition, the antiradical properties of Dendrobium speciosum
(Orchidaceae) leaves and stem extracts have been studied. Furthermore, in view of the use …

Soft tissue sarcomas: new opportunity of treatment with PARP inhibitors?

M Mangoni, M Sottili, G Salvatore, D Campanacci… - La radiologia …, 2019 - Springer
Background Poly (ADP-ribose) polymerases (PARP) are a large family of enzymes involved
in several cellular processes, including DNA single-strand break repair via the base …

Investigation of the Cytotoxic, Genotoxic, and Apoptosis-Inducing Effects of Estragole Isolated from Fennel (Foeniculum vulgare)

M Villarini, R Pagiotti, L Dominici… - Journal of natural …, 2014 - ACS Publications
The present study was undertaken to evaluate, in the HepG2 human hepatoma cell line, the
in vitro cytotoxic, genotoxic, and apoptotic activities of estragole (1), contained in the …

Cyclin-dependent kinase 4/6 inhibitors combined with radiotherapy for patients with metastatic breast cancer

I Ratosa, M Orazem, E Scoccimarro, M Steinacher… - Clinical Breast …, 2020 - Elsevier
Background The cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) represent the standard
treatment for hormone receptor–positive, human epidermal growth factor receptor 2 …

In vitro toxicity evaluation of estragole-containing preparations derived from Foeniculum vulgare Mill.(fennel) on HepG2 cells

S Levorato, L Dominici, C Fatigoni, C Zadra… - Food and chemical …, 2018 - Elsevier
Estragole, a common component of herbs and spices, is a wellknown genotoxic
hepatocarcinogen in rodents, whereas its potential toxic effect in humans is still debated. In …

Evaluation of genotoxic and antigenotoxic effects of hydroalcoholic extracts of Zuccagnia punctata Cav.

IC Zampini, M Villarini, M Moretti, L Dominici… - Journal of …, 2008 - Elsevier
Zuccagnia punctata Cav.(Fabaceae), a widely used plant species in Argentine folk
medicine, has been shown to have a broad spectrum of antibacterial, antifungal, antioxidant …

Thermal Ablation versus SBRT in liver tumours: pros and cons

M Loi, I Desideri, L Dominici, G Francolini, P Garlatti… - Medical Oncology, 2020 - Springer
Non-surgical locally ablative treatments for primary liver cancer and liver metastases
represent an effective therapeutic choice when surgery cannot be performed or is not …