Estimates from Mendelian randomization studies of unrelated individuals can be biased due
to uncontrolled confounding from familial effects. Here we describe methods for within-family …

Background Psoriasis is a common inflammatory skin disease that has been reported to be
associated with obesity. We aimed to investigate a possible causal relationship between …

Objective To investigate the shape of the causal relation between body mass index (BMI)
and mortality. Design Linear and non-linear mendelian randomisation analyses. Setting …

Objectives To study the trajectories of body mass index (BMI) in Norway over five decades
and to assess the differential influence of the obesogenic environment on BMI according to …

Mendelian randomization (MR) is a widely-used method for causal inference using genetic
data. Mendelian randomization studies of unrelated individuals may be susceptible to bias …

Background: Many studies have investigated how unemployment influences health, less
attention has been paid to the reverse causal direction; how health may influence the risk of …

From a life-course perspective, genetic and environmental factors driving childhood obesity
may have a lasting influence on health later in life. However, how obesity trajectories vary …

Objectives To prospectively investigate the association between occupational physical
activity (OPA) and disability pension due to musculoskeletal cause, mental cause or any …

Background Obesity has tripled worldwide since 1975 as environments are becoming more
obesogenic. Our study investigates how changes in population weight and obesity over time …

Background and purpose Headache has been associated with various lifestyle and
psychosocial factors, one of which is smoking. The aim of the present study was to …