Background Susceptibility to asthma is influenced by genes and environment; implicated
genes may indicate pathways for therapeutic intervention. Genetic risk factors may be useful …

Background A genomewide association study has shown an association between variants
at chromosome 17q21 and an increased risk of asthma. To elucidate the relationship …

We examined common variation in asthma risk by conducting a meta-analysis of worldwide
asthma genome-wide association studies (23,948 asthma cases, 118,538 controls) of …

Eczema often precedes the development of asthma in a disease course called the 'atopic
march'. To unravel the genes underlying this characteristic pattern of allergic disease, we …

The role of eosinophils and basophils in allergic diseases c... : Current Opinion in Allergy and
Clinical Immunology The role of eosinophils and basophils in allergic diseases considering …

Rationale: Bronchopulmonary dysplasia is the most common chronic respiratory disease in
premature infants. Genetic factors might contribute to bronchopulmonary dysplasia …

Rationale: It has been shown that country living protects against asthma, which may be
explained by microbial exposures. Objectives: To study whether single nucleotide …

Background Low circulating vitamin D levels have been associated with risk of asthma,
atopic dermatitis, and elevated total immunoglobulin E (IgE). These epidemiological …

Single nucleotide polymorphisms (SNPs) at chromosome 17q21 confer an increased risk of
early-onset asthma. The objective was to study whether 17q21 SNPs modify associations …

Background Transient receptor potential (TRP) vanilloid and ankyrin cation channels are
activated by various noxious chemicals and may play an important role in the pathogenesis …