Study of sperm characteristics in persons occupationally exposed to lead

Am J Ind Med. 1992;22(4):567-71. doi: 10.1002/ajim.4700220411.

Abstract

The sperm characteristics of 38 male workers exposed to lead in a battery factory were studied. Sperm analysis was performed after 4 days of sexual abstinence. Parameters analyzed were: volume, sperm count, motility, and morphology. Exposure levels were estimated by measuring the concentration of lead and delta-aminolevulinic acid in the serum. Based on blood lead levels, the tested individuals were divided in three groups: A (12), B (11), and C (15). Significant levels of asthenospermia and teratospermia were found in exposed workers when compared with unexposed controls. Long-term exposure to lead may lead to changes in sperm characteristics and function.

MeSH terms

  • Adult
  • Humans
  • Lead / adverse effects*
  • Lead / pharmacokinetics
  • Lead Poisoning / blood
  • Lead Poisoning / etiology*
  • Male
  • Occupational Diseases / blood
  • Occupational Diseases / etiology*
  • Occupational Exposure / adverse effects*
  • Sperm Count / drug effects*
  • Sperm Motility / drug effects*
  • Spermatogenesis / drug effects*

Substances

  • Lead