Abstract
This work focuses on the neurophysiological features in a patient with action myoclonus and mental deterioration following methylbromide intoxication. The patient is a 28-year-old man, without respiratory distress or exposure to other toxics. Myoclonus improved with polytherapy (clonazepam, 5-HT, carbidopa, GABA). The neurophysiological and neuropsychological evidence in this patient suggests a possible double site of action of methylbromide at cortical and subcortical levels.
MeSH terms
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Adult
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Carbidopa / administration & dosage
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Clonazepam / administration & dosage
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Drug Therapy, Combination
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Electroencephalography / drug effects
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Epilepsies, Myoclonic / chemically induced
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Epilepsies, Myoclonic / diagnosis
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Epilepsies, Myoclonic / psychology
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Epilepsy, Tonic-Clonic / chemically induced
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Epilepsy, Tonic-Clonic / diagnosis
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Epilepsy, Tonic-Clonic / psychology
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Evoked Potentials / drug effects
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Humans
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Hydrocarbons, Brominated / poisoning*
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Male
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Myoclonus / chemically induced*
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Myoclonus / diagnosis
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Myoclonus / psychology
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Reaction Time / drug effects
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Substance-Related Disorders / diagnosis*
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Substance-Related Disorders / psychology
Substances
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Hydrocarbons, Brominated
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Clonazepam
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methyl bromide
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Carbidopa