Journal of Pediatric Surgery Electronic Pages
Maternal exposure to diethylene glycol monomethyl ether: A possible role in the etiology of retrocaval ureter☆

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Abstract

Retrocaval ureter is a very rare condition. In light of the experimental studies, one of the etiologic factors seems to be maternal contact with diethylene glycol monomethyl ether or ethylene glycol monomethyl ether. A case of cardiovascular, skeletal, and retrocaval ureter anomalies caused by possible maternal contact while pregnant with these materials at her work in a textile factory is presented. J Pediatr Surg 37:E23. Copyright 2002, Elsevier Science (USA). All rights reserved.

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Case report

A 5-year-old boy, whose mother worked in a local weaving company in the thread-dying section with direct exposure to dyes during the last 7 years, underwent prograde right and transseptal left heart catheterization for ventricular septal defect (VSD). After the procedure, a routine abdominal plain radiograph was taken, and significant hydronephrosis of the right kidney caused by an obstructed right ureter was noted as an incidental finding. In addition, there was a duplicated collecting system

Discussion

Retrocaval ureter is a rare congenital anomaly and generally is regarded as resulting from abnormal development of the inferior vena cava (IVC) rather than the ureter and having a prevalence of 0.1%.4 During fetal development, the more ventral subcardinal vein does not regress and instead develops into the infrarenal segment of the vena cava. In this stituation, the more dorsally located ureter passes behind and around the vena cava as the developing metanephros ascends to its lumbar location

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Address reprint requests to Mesut Gurdal, MD, Semsettin Gunaltay cd. 268/4, 81080 Erenkoy-Istanbul/Turkey.

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