Public healthLobar pneumonia: an occupational disease in welders
References (18)
Occupational lung disorders
(1982)- (1958)
- et al.
Respiratory hazards in welding
Ann Occup Hyg
(1964) Decennial supplement England and Wales 1961 occupational mortality tables
(1971)Occupational mortality
(1970-72)Classification of occupations 1980
(1980)Occupational mortality in Washington State 1950-79
(1983)Mortality among welders, including a group exposed to nickel oxides
Arch Environ Health
(1981)
Cited by (106)
Metals and the respiratory tract
2021, Handbook on the Toxicology of Metals: Fifth EditionMetals and the respiratory tract
2021, Handbook on the Toxicology of Metals: Volume I: General ConsiderationsA proteome-wide assessment of the oxidative stress paradigm for metal and metal-oxide nanomaterials in human macrophages
2020, NanoImpactCitation Excerpt :However, this approach must be balanced with the reality that typical human exposures to ENMs will be at low doses and occur in the context of mixed exposures to additional environmental challenges, such as bacteria. The important question of whether adverse effects of ENMs may be manifested by altering susceptibility to concurrent environmental exposures is often overlooked, despite mounting evidence that important health impact from environmental and occupational nanoparticle exposures in humans include indirect effects such as suppressed innate immune function (Andujar et al., 2014; Coggon et al., 1994; Neupane et al., 2010; Palmer et al., 2003; Thrall et al., 2019). Identification of the biological pathways and proteins that are broadly affected by ENMs, such as cell adhesion proteins that are also critical for normal macrophage function, can provide insight into the molecular mechanisms by ENM exposures may alter susceptibility to other environmental challenges.
Modulation of susceptibility to lung bacterial infection by engineered nanomaterials: In vitro and in vivo correspondence based on macrophage phagocytic function
2019, NanoImpactCitation Excerpt :Although there is limited human data on potential health impacts of engineered particles, decades of research on ambient air particulates have found strong associations between exposure to ultrafine air pollution particles and increased risk of community-acquired pneumonia and other lung infections, particularly in children and the elderly (Loeb et al., 2009; Neupane et al., 2010a,b). Increased risks of pneumonia and morbidity are also observed in welders exposed to fumes that are rich in metal oxide nanoparticles (Coggon et al., 1994; Palmer et al., 2003; Andujar et al., 2014). Up to 80% of airborne particulates from welding operations are submicron-sized particles (Dasch and D'Arcy, 2008; Stephenson et al., 2003), and nano-scale particles (20–25 nm diameter) composed of iron, manganese and chromium oxides have been clearly identified within alveolar macrophages and in fibrous regions of the lung (Andujar et al., 2014).
Inhalation of iron-abundant gas metal arc welding-mild steel fume promotes lung tumors in mice
2018, ToxicologyCitation Excerpt :The immunosuppressive effects of welding fume exposure may be a contributing mechanism for the resulting lung carcinogenesis. Worker studies have indicated that welders are at increased risk of lobar pneumonia from Streptococcus pneumoniae infection as well as other lung infections (Coggon et al., 1994; Coggon and Palmer, 2016; Suri et al., 2016; Zeidler-Erdely et al., 2012). A cross-sectional study of shipyard workers in the Middle East found that those exposed to welding fumes had a higher prevalence of respiratory symptoms and were more likely to report to healthcare professionals concerning respiratory infections (Marongiu et al., 2016).
Occupational lung diseases
2017, Revue des Maladies Respiratoires Actualites