The influence of skin moisture on the dermal absorption of propoxur in human volunteers: a consideration for biological monitoring practices
References (16)
- et al.
Assessment of dermal exposure to chemicals
Sci. Total Environ.
(1995) - et al.
Monitoring of propoxur exposure
- et al.
Determination of 2-isopropoxyphenol (IPP) in urine by capillary gas chromatography and mass-selective detection
J. Chromatogr.
(1992) - et al.
Worker exposure to, and absorption of, cypermethrin during aerial application of an ‘ultra low volume’ formulation to cotton
Arch. Environ. Contam. Toxicol.
(1987) - et al.
Occupational exposure to fosetyl-Al fungicide during spraying of ornamentals in greenhouses
Arch. Environ. Contam. Toxicol.
(1987) - et al.
Skin contamination, airborne concentrations and urinary metabolite excretion of the pesticide propoxur during harvesting of flowers in greenhouses
Am. J. Ind. Med.
(1993) - et al.
Dose-excretion study with the insecticide propoxur in volunteers
- et al.
Determination of efficiency for exposure reduction of protective clothing by biological monitoring in a field study
Cited by (49)
Perspiration promotes the effect of sulphite on the shielding response of rodent skin
2021, HeliyonCitation Excerpt :Sweating is the process of releasing fluids to regulate body temperature. Perspiration replenishes moisture on the skin to maintain surface protection; however, skin moisture (which is influenced by relative humidity) is also a key determinant of human exposure that results in the increased dermal absorption of pesticides such as propoxur and chlorpyrifos (Williams et al., 2004; Meuling et al., 1997). Studies have delineated the association of skin conditions with air pollution and perspiration, but none have focused on how perspiration influences the response of the skin to air pollutant exposure.
The presence of licit and illicit drugs in police stations and their implications for workplace drug testing
2017, Forensic Science InternationalCitation Excerpt :However, drugs tend to contain functional groups that tend to be charged to improve water solubility and may require an ion pair to improve skin absorption [37]. This may be by increased by improved skin hydration resulting from increased environmental humidity, allowing greater penetration of foreign organic molecules [38]. Additionally, organic chemical penetration of skin suffering sunburn and abrasions has been shown to increase over undamaged skin, with the greatest increase in penetration occurring observed for molecules with low rates of absorption [39].
Uptake and elimination of permethrin related to the use of permethrin treated clothing for forestry workers
2014, Toxicology LettersCitation Excerpt :Furthermore, skin hydration, which might also be affected by external climate conditions, seems to be an important factor influencing dermal penetration. As demonstrated by (Meuling et al., 1997) in volunteers dermally exposed to the pesticide propoxur, the percentage of the body burden attributable to dermal absorption increased from 13% to 63% with increasing relative humidity at 30 °C from 50 to 63%. Since the exposure conditions in our study induced perspiration of the participants, this may have additionally increased skin hydration.
Variability of biomarkers in volunteer studies: The biological component
2010, Toxicology LettersThe greenhouse work environment: a modifier of occupational pesticide exposure?
2019, Journal of Environmental Science and Health - Part B Pesticides, Food Contaminants, and Agricultural Wastes