Male-mediated F1 effects in mice exposed to 1,3-butadiene
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Male-mediated F1 effect in mice exposed to 1,3-butadiene
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Cited by (19)
A reproductive and developmental toxicity screening study of 1,3-butadiene in Sprague-Dawley rats
2021, Regulatory Toxicology and PharmacologyCitation Excerpt :Thus, the current study exposed rats to sufficient BD concentrations and exposure durations to ensure that indications of male reproductive toxicity would have been observed if responses were similar to mice. These results are consistent with Anderson et al. (1996, 1998), who reported no effects on the fertility of rats following repeated inhalation exposures to BD. Ovotoxic effects in rats have not been reported with repeat-dose BD exposure (Melnick and Huff, 1992), including the chronic study where female rats were exposed to up to 8000 ppm BD for 6 h/day, 5 days/week for 2 years (Owen et al., 1987).
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2015, Handbook of Fertility: Nutrition, Diet, Lifestyle and Reproductive HealthEvaluation of a Male Reproductive Toxicant
2010, Comprehensive Toxicology, Second EditionThe Male Germ Cell as a Target for Toxicants
2010, Comprehensive Toxicology, Second EditionMale-mediated developmental toxicity
2005, Toxicology and Applied PharmacologyA comparison of male-mediated effects in rats and mice exposed to 1,3- butadiene
1998, Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
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