Changes in motor and sensory nerve conduction parameters with temperature in normal and diseased nerve

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Abstract

The effects of temperature on conventional motor and sensory nerve conduction parameters were studied in normals and in some pathological conditions.

Surface stimulating and recording electrodes were used to examine the function of the median nerve. The motor and sensory conduction velocities, the parameters of compound muscle action and sensory nerve potentials were correlated with skin temperature.

In the control subjects all nerve conduction parameters changed with temperature. These findings were similar to those published previously, but the mean slope for MCV was lower than that reported in the literature. The amplitude values widely scattered as a consequence of methodological factors, which may mask effects of temperature.

Only minor differences were revealed between control subjects and patients. The effect of temperature proved to be similar in the patients and in the normal controls. Therefore, the correction factors determined in normals may be acceptable for abnormal nerves in standardising the measured values with respect to temperature. However, in pathological cases, above all in diabetes mellitus, the slightly reduced changes of conduction velocities vs. temperature may be the source of false negative results in borderline cases when using the normal correction factors. The combination of preserved temperature dependence but decreased conduction velocities may indicate that demyelination and temperature influence the conduction velocities via different mechanisms.

References (28)

  • J.R. Schwarz et al.

    Diphenylhydantoin: excitability reducing action in single myelinated nerve fibers

    Eur. J. Pharmacol.

    (1977)
  • P.D. Swanson et al.

    Diphenylhydantoin and movement of radioactive sodium into electrically stimulated cerebral slices

    Biochem. Pharmacol.

    (1972)
  • C.F. Bolton

    Minimonography no. 17: Factors Affecting the Amplitude of Human Sensory Compound Action Potentials

    (1981)
  • C.F. Bolton et al.

    The effects of temperature on human compound action potentials

    J. Neurol. Neurosurg. Psychiat.

    (1981)
  • C.F. Bolton et al.

    Temperature effects on conduction studies of normal and abnormal nerve

    Muscle Nerve

    (1982)
  • W.F. Brown

    The Physiological and Technical Basis of Electromyography

    (1984)
  • F. Buchthal et al.

    Evoked action potentials and conduction velocity in human sensory nerves

    Brain Res.

    (1966)
  • P.V. De Jesus et al.

    The effect of cold on nerve conduction of human slow and fast nerve fibres

    Neurology

    (1973)
  • R.H. De Jong et al.

    Nerve conduction velocity during hypothermia in man

    Anesthesiology

    (1966)
  • E. Denys

    Minimonograph no. 14: The Role of Temperature in Electromyography

    (1980)
  • J.D. Deupree

    Mode of action of anticonvulsant drugs: membrane effects

  • B. Falck et al.

    The development of a multicenter data base for reference values in clinical neurophysiology — principles and examples

    Computer Meth.

    (1992)
  • A.H.C. Geerlings et al.

    Temperature and nerve conduction velocity, some practical problems

    Electromyogr. Clin. Neurophysiol.

    (1985)
  • J.D. Henricksen

    Conduction velocity of motor nerves in normal subjects and in patients with neurological disorders

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    The study was supported by Swedish Research Council (Grant 135 ES) and by Swedish Institute (Grant to Dr. Peter Dioszeghy).

    1

    This investigation was prompted from a collaborative study with Drs. Arimura and Sonoo, Kagoshima, Japan. We thank them for valuable discussions.

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