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Cardiovascular responses to autonomic stimuli in workers with vibration-induced white finger

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Summary

Cardiovascular responses to autonomic stimulation were assessed in 11 grinding operators affected with vibration-induced white finger (VWF) and in 11 comparable healthy controls by measuring blood pressures, heart rate and systolic time intervals (STI) during a hand-grip test, an arithmetic test and an orthostatic test. Digital circulatory function was also investigated by measurement of finger systolic pressure (FSP) during local cooling with water at 30°C, 15°C and 10°C. The increase in diastolic blood pressure and heart rate during the stress tests was greater in the VWF workers than in the controls. The STI values such as total electromechanical systole and left ventricular ejection time, were found to be shorter in the VWF subjects than in the controls at rest and during both the circulatory stress tests and the recovery periods (0.001<p<0.05). Multiple regression analysis showed that vibration exposure was the major predictor of STI during the stress tests, while age, smoking and drinking habits did not contribute substantially to the explained variation in STI. The reduction in FSP by local cooling from 30°C to 15°C and 10°C was greater in VWF operators than in controls (p<0.001), and total closure of the digital arteries at 10°C was observed in 8 VWF workers (72.7%). In all subjects significant relationships were found between the reduction in FSP at 10°C and the decrease in STI during circulatory stress activities (p<0.001). The findings in this study suggest an association between vibration exposure, digital vasospasm and increased cardiac sympathetic tone, the latter being demonstrated by the shortening of STI during the stress tests. It is suggested that excessive sympathetic reflex activity plays the dominant role in the pathogenesis of VWF.

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References

  • Atterhög JH, Ekelund LG (1980) Significance of primary T wave aberrations in the electrocardiogram of asymptomatic young men. Part III. Systolic time intervals and autonomic tone. Scand J Clin Lab Invest 40:795–803

    PubMed  Google Scholar 

  • Bovenzi M (1986) Some pathophysiological aspects of vibration-induced white finger. Eur J Appl Physiol 55:381–389

    Article  CAS  Google Scholar 

  • Gemne G (1982) Pathophysiology and multifactorial etiology of acquired vasospastic disease (Raynaud syndrome) in vibration-exposed workers. Scand J Work Environ Health 8:243–249

    CAS  PubMed  Google Scholar 

  • Gemne G, Pyykkö I, Taylor W, Pelmear PL (1987) The Stockholm workshop scale for the classification of cold-induced Raynaud's phenomenon in the hand-arm vibration syndrome. (Revision of the Taylor-Pelmear scale.) Scand J Work Environ Health 13:275–278

    CAS  PubMed  Google Scholar 

  • Heinonen E, Färkkilä M, Forsström J, Antila K, Jalonen J, Korhonen O, Pyykkö I (1987) Autonomic neuropathy and vibration exposure in forestry workers. Br J Ind Med 44:412–416

    CAS  PubMed  Google Scholar 

  • Hyvärinen J, Pyykkö I, Sundberg S (1973) Vibration frequencies and amplitudes in the aetiology of traumatic vasospastic disease. Lancet i:791–794

    Google Scholar 

  • Jepson RP (1951) Raynaud's phenomenon: a review of the clinical problem. Ann R Coll Surg Engl 9:35–45

    CAS  PubMed  Google Scholar 

  • Lagerkvist B, Linderholm H, Nordberg G (1986) Vasospastic tendency and Raynaud's phenomenon in smelter workers exposed to arsenic. Environ Res 39:465–474

    Article  CAS  PubMed  Google Scholar 

  • LeBlanc J, Côté J, Jobin M, Labrie A (1979) Plasma catecholamines and cardiovascular responses to cold and mental activity. J Appl Physiol Respir Environ Exerc Physiol 47:1207–1211

    CAS  Google Scholar 

  • Lewis RP, Boudoulas H, Forester WF, Weissler AM (1972) Shortening of electromechanical systole as a manifestation of excessive adrenergic stimulation in acute myocardial infarction. Circulation 48:856–862

    Google Scholar 

  • Lewis RP, Boudoulas H, Welch TG, Forester WF (1976) Usefulness of systolic time intervals in coronary artery disease. Am J Cardiol 37:787–796

    CAS  PubMed  Google Scholar 

  • Lewis T (1929) Experiments relating to the peripheral mechanism involved in spasmodic arrest of the circulation in the fingers. A variety of Raynaud's disease. Heart 15:7–101

    Google Scholar 

  • Lilis R, Anderson H, Nicholson WJ, Daum S, Fischbein AS, Selikoff IJ (1975) Prevalence of disease among vinyl chloride and polyvinyl chloride workers. Ann NY Acad Sci 246:22–41

    CAS  PubMed  Google Scholar 

  • Lindqvist VAY, Spangler RD, Blount SG (1973) A comparison between the effects of dynamic and isometric exercise as evaluated by the systolic time intervals in normal man. Am Heart J 85:227–236

    Google Scholar 

  • Matoba T, Mizobuchi H, Ito T, Chiba M, Toshima H (1981) Further observations of the digital plethysmography in response to auditory stimuli and its clinical applications. Angiology 32:62–72

    CAS  PubMed  Google Scholar 

  • Nielsen SL, Lassen NA (1977) Measurement of digital blood pressure after local cooling. J Appl Physiol 43:907–910

    CAS  PubMed  Google Scholar 

  • Nielsen SL, Lassen NA (1982) Finger systolic pressure in upper extremities testing for cold sensitivity (Raynaud's phenomenon). In: Bernstein EF (ed) Noninvasive diagnostic techniques in vascular disease. Mosby, London, pp 410–416

    Google Scholar 

  • Nielsen SL, Olsen N, Henriksen O (1980) Cold hypersensitivity after sympathectomy for Raynaud's disease. Scand J Thorac Cardiovasc Surg 14:109–111

    CAS  PubMed  Google Scholar 

  • Norusis MJ (1986) SPSS/PCT For the IBM PC/XT/AT. SPSS Inc, Chicago

    Google Scholar 

  • Olsen N (1987) Centrally and locally mediated vasomotor activities in Raynaud's phenomenon. Scand J Work Environ Health 13:309–312

    CAS  PubMed  Google Scholar 

  • Olsen N, Nielsen SL (1979) Diagnosis of Raynaud's phenomenon in quarrymen's traumatic vasospastic disease. Scand J Work Environ Health 5:249–256

    Google Scholar 

  • Olsen N, Nielsen SL, Voss P (1982) Cold response of digital arteries in chain saw operators. Br J Ind Med 39:82–88

    CAS  PubMed  Google Scholar 

  • Olsen N, Fjeldborg P, Brochner-Mortensen J (1985) Sympathetic and local vasoconstrictor response to cold in vibration induced white finger. Br J Ind Med 42:272–275

    CAS  PubMed  Google Scholar 

  • Quarry VM, Spodick DH (1974) Cardiac responses to isometric exercise. Comparative effects with different postures and levels of exertion. Circulation 49:905–920

    CAS  PubMed  Google Scholar 

  • Stafford RW, Harris WS, Weissler AM (1970) Left ventricular systolic time intervals as indices of postural circulatory stress in man. Circulation 41:485–492

    CAS  PubMed  Google Scholar 

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Bovenzi, M. Cardiovascular responses to autonomic stimuli in workers with vibration-induced white finger. Europ. J. Appl. Physiol. 59, 199–208 (1989). https://doi.org/10.1007/BF02386188

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