Exposure | Smoking | Heavy alcohol use | Low physical activity | Obesity | Chronic disease | Psychological distress | |||||||
N | PR | 95% CI | PR | 95% CI | PR | 95% CI | PR | 95% CI | PR | 95% CI | PR | 95% CI | |
Neither | 7 342 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | ||||||
Childhood adversity only | 10 613 | 1.28 | 1.17 to 1.40 | 1.13 | 1.04 to 1.22 | 1.08 | 1.02 to 1.14 | 1.16 | 1.08 to 1.25 | 1.12 | 1.04 to 1.20 | 1.38 | 1.31 to 1.46 |
Low adult SES only | 4 868 | 2.18 | 2.00 to 2.39 | 0.73 | 0.65 to 0.82 | 1.29 | 1.22 to 1.37 | 1.42 | 1.31 to 1.54 | 1.21 | 1.11 to 1.31 | 0.88 | 0.825 to 0.9 |
Both | 8 650 | 2.76 | 2.55 to 2.99 | 0.89 | 0.81 to 0.97 | 1.41 | 1.33 to 1.48 | 1.61 | 1.50 to 1.72 | 1.37 | 1.28 to 1.47 | 1.32 | 1.25 to 1.40 |
Synergy index | 1.20 | 1.02 to 1.41 | 0.77 | 0.29 to 2.00 | 1.10 | 0.86 to 1.42 | 1.04 | 0.80 to 1.34 | 1.15 | 0.77 to 1.72 | 1.22 | 0.84 to 1.77 | |
Job strain | Shift work | Fixed-term contract | |||||||||||
Neither | 7 342 | 1.00 | 1.00 | 1.00 | |||||||||
Childhood adversity only | 10 613 | 1.23 | 1.15 to 1.31 | 1.35 | 1.24 to 1.46 | 1.16 | 1.07 to 1.26 | ||||||
Low adult SES only | 4 868 | 1.90 | 1.77 to 2.03 | 3.20 | 2.96 to 3.46 | 0.70 | 0.62 to 0.79 | ||||||
Both | 8 650 | 2.08 | 1.95 to 2.21 | 3.43 | 3.19 to 3.68 | 0.78 | 0.71 to 0.86 | ||||||
Synergy index | 0.96 | 0.84 to 1.10 | 0.95 | 0.86 to 1.06 | 1.51 | 0.61 to 3.77 |
*Adjusted for age and sex.