Table 4

Exposure–response coefficients from Poisson regression of lung-cancer mortality rates

	Internal adjustment				External adjustment
	Cumulative*		ln Cumulative		Cumulative		ln Cumulative
	Coefficient†	p Value	Coefficient	p Value	Coefficient	p Value	Coefficient	p Value
Exposure unlagged
Including all exposure groups
Original data	0.013	0.543	0.144	0.006	0.017	0.371	0.114	0.008
Revised cohort, mortality and employment data	−0.001	0.951	0.089	0.076	−0.006	0.771	0.063	0.148
Inclusion of additional workers	−0.006	0.761	0.056	0.223	−0.007	0.600	0.043	0.126
Excluding last exposure group
Original data	0.204	0.001	0.230	0.001	0.180	0.002	0.180	0.001
Revised cohort, mortality and employment data	0.172	0.003	0.175	0.004	0.161	0.003	0.167	0.004
Inclusion of additional workers	0.149	0.007	0.126	0.021	0.142	<0.001	0.124	0.007
Exposure lagged 15 years
Including last exposure group
Original data	0.008	0.719	0.106	0.021	0.017	0.402	0.091	0.007
Revised cohort, mortality and employment data	−0.008	0.726	0.077	0.113	−0.010	0.610	0.056	0.180
Inclusion of additional workers	−0.013	0.550	0.049	0.271	−0.011	0.566	0.042	0.282
Excluding last exposure group
Original data	0.204	0.002	0.170	0.001	0.190	0.001	0.144	0.001
Revised cohort, mortality and employment data	0.159	0.009	0.160	0.007	0.153	0.005	0.159	0.004
Inclusion of additional workers	0.136	0.018	0.121	0.025	0.139	0.009	0.127	0.012

*Cumulative exposure (mg/m³/years) included in the model as the mean of each exposure category or the natural logarithm (ln cumulative) of the mean.
†Regression coefficient for the increase in the natural logarithm of relative risk per unit increase in cumulative exposure or its logarithm.