Exposure | ΔFVC (mL) | ΔFEV1 (mL) | ΔDL,CO (mmol/min/Pa) | AR ΔM1 (cm2) | AR ΔV1 (cm3) | AR ΔM2 (cm2) | AR ΔV2 (cm3) |
---|---|---|---|---|---|---|---|
Grain dust (mg/m3) | |||||||
0 (referents) | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
0.09–0.6 | 67 (−60 to 194) | 57 (−46 to 161) | 153 (−238 to 544) | −0.08 (−0.19 to 0.04) | −0.08 (−0.31 to 0.14) | 0.03 (−0.08 to 0.14) | 0.06 (−0.77 to 0.89) |
0.61–1.3 | 65 (−50 to 181) | −27 (−121 to 67) | −87 (−440 to 265) | −0.15 (−0.26 to −0.05) | −0.23 (−0.43 to −0.02) | −0.005 (−0.11 to 0.10) | 0.30 (−0.46 to 1.1) |
1.31–14 | 29 (−84 to 142) | 17 (−76 to 109) | −64 (−410 to 281) | −0.12 (−0.22 to −0.02) | −0.16 (−0.36 to 0.05) | −0.03 (−0.13 to 0.07) | 0.006 (−0.74 to 0.76) |
Endotoxin (EU/m3) | |||||||
0 (referents) | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
15–350 | 46 (−72 to 165) | 11 (−86 to 108) | 235 (−129 to 598) | −0.18 (−0.29 to −0.08) | −0.28 (−0.49 to −0.07) | 0.03 (−0.07 to 0.014) | 0.40 (−0.39 to 1.19) |
360–1000 | 103 (−5 to 211) | 61 (−27 to 149) | −147 (−475 to 181) | −0.10 (−0.20 to 0.004) | −0.15 (−0.34 to 0.05) | −0.002 (−0.10 to 0.09) | −0.06 (−0.78 to 0.67) |
1200–11 000 | −19 (−144 to 106) | −62 (−164 to 40) | −95 (−480 to 289) | −0.08 (−0.19 to 0.04) | −0.05 (−0.28 to 0.17) | −0.05 (−0.15 to 0.06) | 0.09 (−0.74 to 0.91) |
Bacteria (counts/m3) | |||||||
0 (referents) | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
0.28×104–14.99×104 | 65 (−47 to 177) | −14 (−101 to 73) | 191 (−156 to 537) | −0.16 (−0.26 to −0.05) | −0.24 (−0.45 to −0.04) | 0.02 (−0.08 to 0.12) | 0.17 (−0.60 to 0.93) |
15×104–47×104 | 90 (−24 to 204) | 109 (20 to 198) | −37 (−384 to 310) | −0.09 (−0.19 to 0.02) | −0.14 (−0.34 to 0.06) | −0.008 (−0.11 to 0.09) | 0.11 (−0.64 to 0.86) |
58×104–240×104 | −15 (−141 to 110) | −78 (−176 to 20) | −240 (−613 to 133) | −0.11 (0.23 to 0.006) | −0.09 (−0.032 to 0.13) | −0.03 (−0.14 to 0.08) | 0.09 (−0.74 to 0.92) |
Fungal spores (counts/m3) | |||||||
0 (referents) | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
1×104–1.5×104 | 18 (−94 to 130) | 45 (−49 to 138) | 159 (−200 to 518) | −0.10 (−0.20 to 0.01) | −0.15 (−0.36 to 0.06) | 0.01 (−0.09 to 0.11) | 0.08 (−0.67 to 0.83) |
1.6×104–5.4×104 | 143 (29 to 258) | 38 (−57 to 133) | −138 (−497 to 221) | −0.13 (−0.24 to −0.02) | −0.13 (−0.35 to 0−08) | −0.05 (−0.15 to 0.05) | −0.22 (−0.99 to 0.54) |
5.5×104–50×104 | −6 (−123 to 111) | −52 (−150 to 45) | −65 (−424 to 293) | −0.13 (−0.24 to −0.02) | −0.21 (−0.43 to 0.006) | 0.03 (−0.08 to 0.13) | 0.54 (−0.24 to 1.33) |
β-1,3-Glucans (µg/m3) | |||||||
0 (referents) | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
0.30–3.60 | 70 (−46 to 186) | 30 (−66 to 126) | 44 (−318 to 407) | −0.13 (−0.24 to −0.02) | −0.17 (−0.39 to 0.04) | 0.08 (−0.02 to 0.18) | 0.51 (−0.25 to 1.28) |
3.70–18.8 | 86 (−21 to 194) | 31 (−59 to 120) | 19 (−322 to 360) | −0.11 (−0.22 to −0.01) | −0.20 (−0.40 to −0.01) | −0.08 (−0.17 to 0.009) | −0.26 (−0.97 to 0.45) |
19.0–150 | −29 (−158 to 100) | −139 (−531 to 254) | −104 (−500 to 290) | −0.12 (−0.24 to 0.004) | −0.09 (−0.32 to 0.14) | 0.01 (−0.10 to 0.12) | 0.24 (−0.60 to 1.08) |
Values are presented as coefficients (95% CI). Bold values indicate p≤0.05.
*Workers without RPE were selected (n=92).
AR, acoustic rhinometry; ΔFEV1, difference in forced expired volume in the first second; ΔFVC, difference in forced vital capacity; ΔDL,CO, difference in CO diffusion capacity of the lung; RPE, respiratory protective equipment.