Panel B: Females: lung cancer cases born since 1940 and mesothelioma cases born since 1925. (The 11 mesotheliomas in women born 1925–1939 are included and also shown in brackets.) | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Highest occupational exposure category | Asbestos lung burden (million fibres per dry gram) | Meso OR vs population controls* | Mean asbestos lung burden (million fibres per dry gram) | ||||||||||
0− | 0.025− | 0.05− | 0.2− | 0.5− | ≥1.0 | Total | Amosite | Crocidolite | Other amphiboles | Chrysotile | All asbestos | ||
High−risk occupations | |||||||||||||
Mesothelioma | 1 (1) | 1 (1) | 0 | 0 | 2 (2) | 4.8 | 0.025 | 0.000 | 0.000 | 0.000 | 0.025 | ||
Lung cancer | 3 | 1 | 0 | 0 | 4 | 0.010 | 0.000 | 0.000 | 0.003 | 0.013 | |||
Medium risk industrial | |||||||||||||
Mesothelioma | 5 (1) | 1 (1) | 1 | 0 | 7 (2) | 2.4 | 0.004 | 0.027 | 0.003 | 0.000 | 0.034 | ||
Lung cancer | 20 | 1 | 4 | 0 | 25 | 0.012 | 0.002 | 0.003 | 0.002 | 0.019 | |||
Domestic exposure | |||||||||||||
Mesothelioma | 2 (2) | 0 | 2 (1) | 3 (1) | 7 (4) | 1.9 | 0.103 | 0.077 | 0.004 | 0.003 | 0.186 | ||
Lung cancer | 13 | 6 | 0 | 1 | 20 | 0.018 | 0.006 | 0.002 | 0.001 | 0.027 | |||
Low-risk occupations | |||||||||||||
Mesothelioma | 5 (1) | 0 | 4 (1) | 1 (1) | 10 (3) | 1.0 (ref) | 0.067 | 0.017 | 0.001 | 0.003 | 0.087 | ||
Lung cancer | 26 | 3 | 2 | 0 | 31 | 0.009 | 0.002 | 0.002 | 0.001 | 0.013 | |||
Total | |||||||||||||
Mesothelioma | 13 (5) | 2 (2) | 7 (2) | 4 (2) | 26 (11) | 0.056 | 0.034 | 0.002 | 0.002 | 0.095 | |||
Lung cancer | 62 | 11 | 6 | 1 | 80 | 0.012 | 0.003 | 0.003 | 0.001 | 0.019 |
*Female mesothelioma ORs from the original case–control study.1