HRs from Andersen–Gill models with piecewise exponential baseline hazard and employee-level frailty term of time-varying disease status
| Variable | Base model | Heart disease | Hypertension | Diabetes | Depress-ion | Asthma |
|---|---|---|---|---|---|---|
| HR (95% CI)p value | HR (95% CI)p value | HR (95% CI)p value | HR (95% CI)p value | HR (95% CI)p value | HR (95% CI)p value | |
| Comorbidities | ||||||
| Any comorbidity | ||||||
| Heart disease | 1.23 (1.11 to 1.36)*** | |||||
| Hypertension | 0.97 (0.92 to 1.02) | |||||
| Diabetes | 1.17 (1.08 to 1.27)*** | |||||
| Depression | 1.25 (1.12 to 1.38)*** | |||||
| Asthma | 1.14 (1.02 to 1.27)* | |||||
| Calendar year (ref is 1997) | *** | *** | *** | *** | *** | *** |
| 1998 | 0.94 (0.83 to 1.06) | 0.93 (0.83 to 1.06) | 0.94 (0.83 to 1.06) | 0.93 (0.83 to 1.06) | 0.93 (0.83 to 1.05) | 0.93 (0.83 to 1.06) |
| 1999 | 0.83 (0.74 to 0.94) | 0.83 (0.74 to 0.94) | 0.83 (0.74 to 0.94) | 0.83 (0.74 to 0.94) | 0.83 (0.74 to 0.94) | 0.83 (0.74 to 0.94) |
| 2000 | 0.92 (0.81 to 1.04) | 0.91 (0.81 to 1.03) | 0.92 (0.81 to 1.04) | 0.92 (0.81 to 1.03) | 0.91 (0.81 to 1.03) | 0.92 (0.81 to 1.03) |
| 2001 | 0.49 (0.43 to 0.56) | 0.49 (0.43 to 0.55) | 0.49 (0.43 to 0.56) | 0.49 (0.43 to 0.55) | 0.49 (0.43 to 0.55) | 0.49 (0.43 to 0.55) |
| 2002 | 0.52 (0.46 to 0.59) | 0.52 (0.46 to 0.58) | 0.52 (0.46 to 0.59) | 0.52 (0.46 to 0.59) | 0.52 (0.46 to 0.58) | 0.52 (0.46 to 0.59) |
| 2003 | 0.48 (0.43 to 0.54) | 0.48 (0.42 to 0.54) | 0.48 (0.43 to 0.55) | 0.48 (0.42 to 0.54) | 0.48 (0.42 to 0.54) | 0.48 (0.42 to 0.54) |
| 2004 | 0.55 (0.48 to 0.62) | 0.54 (0.48 to 0.62) | 0.55 (0.49 to 0.62) | 0.54 (0.48 to 0.62) | 0.54 (0.48 to 0.61) | 0.55 (0.48 to 0.62) |
| 2005 | 0.57 (0.50 to 0.64) | 0.57 (0.50 to 0.64) | 0.57 (0.50 to 0.64) | 0.57 (0.50 to 0.64) | 0.56 (0.50 to 0.64) | 0.57 (0.50 to 0.64) |
| 2006 | 0.50 (0.44 to 0.56) | 0.50 (0.44 to 0.56) | 0.50 (0.44 to 0.56) | 0.50 (0.44 to 0.56) | 0.49 (0.44 to 0.56) | 0.50 (0.44 to 0.56) |
| 2007 | 0.47 (0.42 to 0.53) | 0.47 (0.41 to 0.53) | 0.47 (0.42 to 0.53) | 0.47 (0.41 to 0.53) | 0.47 (0.41 to 0.53) | 0.47 (0.41 to 0.53) |
| First 12 months on the job (inexperienced) | 1.22 (1.17 to 1.26)*** | 1.22 (1.18 to 1.26)*** | 1.21 (1.17 to 1.26)*** | 1.22 (1.18 to 1.26)*** | 1.22 (1.18 to 1.26)*** | 1.22 (1.18 to 1.26)*** |
| Non-white ethnicity | 1.05 (1.00 to 1.10)* | 1.05 (1.00 to 1.10)* | 1.05 (1.00 to 1.10) | 1.04 (0.99 to 1.09) | 1.05 (1.00 to 1.10)* | 1.05 (1.00 to 1.10)* |
| Male gender | 0.74 (0.70 to 0.78)*** | 0.73 (0.70 to 0.77)*** | 0.74 (0.70 to 0.78)* | 0.74 (0.70 to 0.77)*** | 0.74 (0.71 to 0.78)*** | 0.74 (0.70 to 0.78)*** |
| First job at company | 1.01 (0.96 to 1.06) | 1.01 (0.96 to 1.06) | 1.01 (0.96 to 1.06) | 1.01 (0.96 to 1.06) | 1.01 (0.96 to 1.06) | 1.01 (0.96 to 1.06) |
| Age at start of job | 0.98 (0.98 to 0.98)*** | 0.98 (0.98 to 0.98)*** | 0.98 (0.98 to 0.98)*** | 0.98 (0.98 to 0.98)*** | 0.98 (0.98 to 0.98)*** | 0.98 (0.98 to 0.98)*** |
| Smelter plant | 1.40 (1.33 to 1.47)*** | 1.40 (1.33 to 1.47)*** | 1.40 (1.33 to 1.47)*** | 1.40 (1.33 to 1.47)*** | 1.40 (1.33 to 1.47)*** | 1.40 (1.33 to 1.47)*** |
| Union plant | 1.52 (1.42 to 1.63)*** | 1.52 (1.42 to 1.64)*** | 1.52 (1.41 to 1.63)*** | 1.52 (1.41 to 1.63)*** | 1.52 (1.41 to 1.63)*** | 1.52 (1.42 to 1.64)*** |
| Original plant | 1.05 (0.98 to 1.12) | 1.05 (0.98 to 1.12) | 1.05 (0.98 to 1.12) | 1.05 (0.98 to 1.12) | 1.05 (0.98 to 1.12) | 1.05 (0.98 to 1.12) |
| Frailty at employee level | 0.99 (0.94 to 1.05) | 0.99 (0.94 to 1.05) | 0.99 (0.94 to 1.05) | 0.99 (0.93 to 1.05) | 0.99 (0.93 to 1.05) | 0.99 (0.94 to 1.05) |
* p Value less than 0.001.
** p Value less than 0.01.
***p Value less than 0.05.