Demographic characteristics of the cohort
| Males | Females | |||
|---|---|---|---|---|
| Woodworkers n=683 | Control workers n=50 | Woodworkers n=134 | Control workers n=86 | |
| Age at BL years | 39.0 (11.0) | 42.0 (10.7) | 39.0 (9.3) | 37.2 (8.7) |
| Height, cm | 179.2 (7.0) | 177.8 (7.4) | 166.7 (6.0) | 167.6 (5.4) |
| Weight gain, kg | 2.2 (5.5) | 1.7 (6.1) | 1.7 (6.6) | 2.7 (6.0) |
| Missing | 2 | 0 | 1 | 1 |
| Smokers† | 285 (42.0) | 23 (46.0) | 62 (47.0) | 46 (54.1) |
| Missing | 4 | 0 | 2 | 1 |
| Smoking history | ||||
| <7 pack-years‡ | 142 (22.2) | 14 (29.8) | 35 (28.5) | 21 (25.9) |
| ≥7 pack-years‡ | 104 (16.3) | 6 (12.8) | 18 (14.6) | 21 (25.9) |
| Missing | 43 | 3 | 11 | 5 |
| Any respiratory symptom at BL | 250 (40.7) | 20 (43.5) | 48 (41.7) | 27 (35.5) |
| Missing | 69 | 4 | 19 | 10 |
| Chronic Bronchitis at BL | 65 (10.9) | 6 (13.6) | 5 (4.5) | 5 (6.6) |
| Missing | 86 | 6 | 23 | 10 |
| Asthma§ at BL | 34 (5.2) | 3 (6.1) | 10 (7.9) | 5 (6.1) |
| Missing | 25 | 1 | 7 | 4 |
| FEV1% of pred. BL | 98.4±12.0 | 99.8±13.2 | 100.5±13.8 | 100.9±12.5 |
| Missing | 6 | 0 | 1 | 0 |
| Follow-up time years | 6.34 (0.58) | 6.32 (0.27) | 6.31 (0.57) | 6.32 (0.24) |
| Atopy at follow-up¶ | 104 (19.9) | 10 (27.0) | 14 (13.7) | 10 (14.1) |
| Missing | 160 | 13 | 32 | 15 |
| Wood dust at BL** mg/m3 | 0.96 (0.17–0.78) | 0.97 (0.17–3.78) | ||
| Missing | 45 | 7 | ||
| Cumulative wood dust** mg year/m3 | 3.81 (0–7.07)* | 3.26 (0–6.87) | ||
| Missing | 42 | 10 | ||
Data are presented as mean±SD or n (%) of valid cases unless otherwise stated.
*p<0.01 male versus female subjects.
†Smokers are current smokers and ex-smokers who stopped smoking<2 years prior to baseline.
‡Pack-years smoking during follow-up calculated as pack-years at follow-up minus pack-years at baseline.
§Self-reported asthma.
¶Phadiatop was available for a subcohort of 733 participants.
**Median (range).
BL, baseline; FEV1, forced expiratory volume in 1 s; pred., predicted.