Association of cumulative exposure to metalworking fluid with ischaemic heart disease mortality in autoworkers by race and gender
| Cumulative metalworking fluid exposure type and amount (mg/m3-year) | White males | Black males | White females | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Number of cases | Number of person-years | HR* | (95% CI) | Number of cases | Number of person-years | HR* | (95% CI) | Number of cases | Number of person-years | HR* | (95% CI) | |
| Soluble | ||||||||||||
| 0 | 204 | 89 559 | 1.00 | 21 | 17 953 | 1.00 | 6 | 14 693 | 1.00 | |||
| 0–0.76 | 321 | 181 002 | 1.01 | 0.85 to 1.21 | 33 | 34 343 | 1.16 | 0.67 to 2.01 | 28 | 33 175 | 1.84 | 0.76 to 4.50 |
| 0.77–1.80 | 388 | 157 196 | 1.00 | 0.84 to 1.19 | 25 | 21 635 | 0.96 | 0.54 to 1.73 | 29 | 16 045 | 2.40 | 0.97 to 5.91 |
| 1.81–3.44 | 362 | 112 165 | 0.94 | 0.78 to 1.12 | 44 | 19 699 | 1.33 | 0.79 to 2.24 | 27 | 8691 | 2.44 | 0.96 to 6.22 |
| >3.44 | 971 | 177 784 | 1.01 | 0.87 to 1.18 | 172 | 54 600 | 1.01 | 0.64 to 1.61 | 29 | 7929 | 1.89 | 0.74 to 4.86 |
| Synthetic | ||||||||||||
| 0 | 1449 | 485 431 | 1.00 | 275 | 127 499 | 1.00 | 64 | 53 464 | 1.00 | |||
| 0–0.65 | 543 | 173 166 | 1.01 | 0.90 to 1.13 | 10 | 17 740 | 1.38 | 0.64 to 2.97 | 30 | 19 764 | 1.29 | 0.80 to 2.07 |
| >0.65 | 254 | 59 110 | 0.92 | 0.79 to 1.06 | 10 | 2991 | 3.29 | 1.49 to 7.31 | 25 | 7305 | 1.37 | 0.82 to 2.29 |
*Adjusted for type of metalworking fluid, manufacturing plant, year and age (as time metric).