Association of liver and kidney cancer, non-Hodgkin's lymphoma (NHL) and multiple myeloma (MM) by tertiles of cumulative exposure*
| Exposure tertile | Liver | Kidney | NHL | MM | ||||
|---|---|---|---|---|---|---|---|---|
| N† | HR (95% CI) | N† | HR (95% CI) | N† | HR (95% CI) | N† | HR (95% CI) | |
| Ionising radiation‡ | ||||||||
| First | 45 | 1.20 (0.86 to 1.66) | 114 | 0.91 (0.74 to 1.11) | 104 | 0.98 (0.79 to 1.21) | 52 | 1.03 (0.77 to 1.39) |
| Second | 39 | 1.03 (0.73 to 1.45) | 114 | 0.91 (0.74 to 1.11) | 99 | 0.94 (0.75 to 1.16) | 57 | 1.14 (0.86 to 1.52) |
| Third | 51 | 1.35 (0.99 to 1.84) | 129 | 1.02 (0.85 to 1.24) | 109 | 1.03 (0.84 to 1.26) | 62 | 1.23 (0.93 to 1.62) |
| Benzene§ | ||||||||
| First | 373 | 1.00 (0.89 to 1.12) | 1359 | 1.00 (0.94 to 1.06) | 1259 | 0.99 (0.93 to 1.06) | 584 | 1.01 (0.92 to 1.11) |
| 2nd | 497 | 1.04 (0.94 to 1.15) | 1435 | 1.00 (0.95 to 1.06) | 1289 | 1.01 (0.95 to 1.07) | 663 | 1.00 (0.92 to 1.09) |
| 3rd | 485 | 1.14 (1.03 to 1.26) | 1560 | 1.06 (1.00 to 1.12) | 1212 | 0.97 (0.91 to 1.04) | 577 | 0.93 (0.85 to 1.02) |
| Trichloroethylene¶ | ||||||||
| First | 340 | 1.03 (0.91 to 1.16) | 1217 | 1.01 (0.95 to 1.07) | 1213 | 1.01 (0.95 to 1.07) | 468 | 0.93 (0.84 to 1.03) |
| Second | 508 | 0.99 (0.90 to 1.09) | 1556 | 1.02 (0.97 to 1.08) | 1183 | 0.93 (0.88 to 1.00) | 574 | 0.92 (0.84 to 1.01) |
| Third | 422 | 1.00 (0.90 to 1.11) | 1372 | 1.00 (0.95 to 1.07) | 1211 | 0.97 (0.91 to 1.03) | 541 | 0.96 (0.88 to 1.06) |
| Perchloroethylene** | ||||||||
| First | 90 | 0.91 (0.73 to 1.14) | 375 | 1.11 (0.99 to 1.24) | 346 | 1.06 (0.94 to 1.19) | 149 | 0.99 (0.83 to 1.18) |
| Second | 121 | 1.18 (0.97 to 1.44) | 333 | 0.96 (0.86 to 1.08) | 337 | 1.04 (0.93 to 1.17) | 140 | 0.93 (0.78 to 1.12) |
| Third | 114 | 1.13 (0.92 to 1.38) | 314 | 0.94 (0.83 to 1.06) | 292 | 0.95 (0.84 to 1.08) | 148 | 0.98 (0.82 to 1.17) |
*Occupationally unexposed individuals were used as a reference group in all analyses.
†Number of exposed cases.
‡Median exposure (unit-years) first tertile: 0.01 (liver), 0.01 (kidney), 0.01 (NHL), 0.01 (MM); second tertile: 0.03 (liver), 0.03 (kidney), 0.03 (NHL), 0.03 (MM); third tertile: 0.05 (liver), 0.05 (kidney), 0.05 (NHL), 0.06 (MM).
§Median exposure (unit-years) first tertile: 0.01 (liver), 0.01 (kidney), 0.00 (NHL), 0.01 (MM); second tertile: 0.04 (liver), 0.04 (kidney), 0.03 (NHL), 0.04 (MM); third tertile: 0.09 (liver), 0.09 (kidney), 0.09 (NHL), 0.09 (MM).
¶Median exposure (unit-years) first tertile: 0.04 (liver), 0.04 (kidney), 0.04 (NHL), 0.04 (MM); second tertile: 0.25 (liver), 0.13 (kidney), 0.12 (NHL), 0.13 (MM); third tertile: 0.77 (liver), 0.72 (kidney), 0.72 (NHL),0.74 (MM).
**Median exposure (unit-years) first tertile: 0.03 (liver), 0.03 (kidney), 0.02 (NHL), 0.03 (MM); second tertile: 0.12 (liver), 0.12 (kidney), 0.12 (NHL), 0.12 (MM); third tertile: 0.77 (liver), 0.77 (kidney), 0.77 (NHL),0.77 (MM).