Solvent | B-NHL | T-lymphoma | Hodgkin's lymphoma | DLBCL | Follicular lymphoma | CLL | Multiple myeloma |
Case/controls OR 95% CI | Case/controls OR 95% CI | Case/controls OR 95% CI | Case/controls OR 95% CI | Case/controls OR 95% CI | Case/controls OR 95% CI | Case/controls OR 95% CI | |
Unexposed | 1061/1451 1.0 - | 78/1451 1.0 - | 195/1451 1.0 - | 325/1451 1.0 - | 140/1451 1.0 - | 217 /1451 1.0 - | 160/1451 1.0 - |
All solvents: ever exposed | 808/1009 1.1 1.0 to 1.3 | 55/1009 0.9 0.7 to 1.4 | 144/1009 1.1 0.9 to 1.4 | 213/1009 1.0 0.8-1.2 | 111/1009 1.3 1.0 to 1.7 | 196/1009 1.3 1.1 to 1.6 | 117/1009 1.1 0.8 to 1.4 |
Test for trend (p) | 0.000189 | 0.239400 | 0.072352 | 0.491244 | 0.000644 | 0.000004 | 0.056672 |
BTX: ever exposed | 343/402 1.2 1.0 to 1.4 | 30/402 1.3 0.8 to 2.1 | 49/402 1.0 0.7 to 1.4 | 91/402 1.0 0.8-1.4 | 53/402 1.7 1.2 to 2.5 | 86/402 1.4 1.0 to 1.9 | 50/402 1.1 0.8 to 1.6 |
Test for trend (p) | 0.000500 | 0.007425 | 0.397296 | 0.623904 | 0.0000004 | 0.000048 | 0.075480 |
CAH: ever exposed | 284/370 1.1 0.9 to 1.3 | 20/370 1.0 0.6 to 1.7 | 42/370 0.9 0.6 to 1.4 | 68/370 0.8 0.6 to 1.1 | 44/370 1.5 1.0 to 2.2 | 74/370 1.4 1.0 to 1.9 | 38/370 0.9 0.6 to 1.3 |
Test for trend (p) | 0.034276 | 0.784827 | 0.461916 | 0.078624 | 0.000162 | 0.005016 | 0.272958 |
Gasoline: ever exposed | 353/439 1.1 0.9 to 1.3 | 24/439 1.1 0.6 to 1.8 | 46/439 0.7 0.5 to 1.1 | 91/439 0.9 0.7-1.2 | 33/439 1.0 0.6 to 1.6 | 84/439 1.3 0.9 to 1.8 | 60/439 1.2 0.8 to 1.7 |
Test for trend (p) | 0.000405 | 0.079680 | 0.027000 | 0.354000 | 0.177660 | 0.000084 | 0.002070 |
Mineral spirit: ever exposed | 240/317 1.0 0.9 to 1.3 | 22/317 1.2 0.7 to 2.0 | 43/317 1.1 0.7 to 1.6 | 63/317 0.9 0.7-1.2 | 30/317 1.2 0.8 to 1.9 | 56/317 1.2 0.8 to 1.6 | 41/317 1.2 0.8 to 1.7 |
Test for trend (p) | 0.083249 | 0.005520 | 0.480004 | 0.480200 | 0.151767 | 0.028800 | 0.017612 |
Styrene: ever exposed | 66/58 1.6 1.1 to 2.3 | 2/58 0.6 0.1 to 2.7 | 10/58 1.1 0.5 to 2.3 | 20/58 1.5 0.9-2.5 | 11/58 2.6 1.3 to 5.2 | 10/58 1.2 0.6 to 2.5 | 6/58 0.9 0.4 to 2.2 |
Test for trend (p) | 0.000096 | 0.474815 | 0.700728 | 0. 004158 | 0.000097 | 0.268464 | 0.511200 |
Other solvents: ever exposed | 369/449 1.2 1.0 to 1.4 | 25/449 1.0 0.6 to 1.6 | 75/449 1.2 0.9 to 1.6 | 120/449 1.2 1.0-1.6 | 59/449 1.5 1.1 to 2.0 | 88/449 1.5 1.1 to 2.0 | 52/449 1.1 0.8 to 1.5 |
Test for trend (p) | 0.000130 | 0.308884 | 0.005720 | 0. 000144 | 0.000266 | 0.000002 | 0.029240 |
For each association, the α error probability (p) associated with positive trends in risk by three independent exposure metrics (Wald tests for trend) is also shown (see text). p≤0.000125 was defined as the threshold to reject the null hypothesis.
BTX, benzene, toluene and xylene combined; B-NHL, B-cell non-Hodgkin's lymphoma; CAH, chlorinated aliphatic hydrocarbons; CLL, chronic lymphocytic leukaemia; DLBCL, diffuse large B-cell lymphoma.