Preterm birth and major malformations for working with radiolabelling or radioimmunoassay according to exposure levels, among laboratory technicians (n = 991)
| Work process and exposure level | Births, n | Preterm birth | “Major” malformations | ||||
|---|---|---|---|---|---|---|---|
| n (%) | Crude OR | Adjusted OR (95% CI) | n (%) | Crude HR | Adjusted HR (95% CI) | ||
| Logistic regression for preterm birth, OR: odds ratio; Cox regression for major malformations, HR: hazard ratio; adjusted for maternal age, gravidity, history of spontaneous abortion, prepregnancy body mass index, smoking, alcohol consumption, paternal job, and sex of child; CI: confidence interval; numbers for each exposure do not add to n = 991 due to missing. | |||||||
| *Less frequently: work with the process several days per month or more rare. | |||||||
| †Frequently: work with the process every day or several times per week. | |||||||
| Radiolabelling | |||||||
| No | 891 | 34 (3.8) | 1.0 | 1.0 | 47 (5.3) | 1.0 | 1.0 |
| Less frequently* | 55 | 3 (5.5) | 1.5 | 1.2 (0.3 to 4.2) | 5 (9.1) | 1.7 | 1.8 (0.7 to 4.5) |
| Frequently† | 40 | 4 (10.0) | 2.8 | 3.5 (1.1 to 11.0) | 4 (10.0) | 1.9 | 1.8 (0.7 to 5.1) |
| Test for trend | (p = 0.047) | (p = 0.126) | |||||
| Radioimmunoassay | |||||||
| No | 926 | 36 (3.9) | 1.0 | 1.0 | 49 (5.3) | 1.0 | 1.0 |
| Less frequently* | 32 | 1 (3.1) | 0.8 | 0.7 (0.1 to 5.3) | 4 (12.5) | 2.4 | 2.3 (0.8 to 6.6) |
| Frequently† | 29 | 4 (13.8) | 4.0 | 4.8 (1.5 to 15.3) | 3 (10.3) | 1.9 | 1.9 (0.6 to 6.2) |
| Test for trend | (p = 0.026) | (p = 0.099) | |||||