Concentration of plasma NO, and urinary 1-OHPG and 8-OHdG measured for exposed and reference groups by smoking status
| Exposed group | Reference group | p value* | |||
|---|---|---|---|---|---|
| n | Mean (SD) | n | Mean (SD) | ||
| Values shown are mean (SD). | |||||
| *Comparison between the exposed and reference groups. | |||||
| †Comparison between the smokers and non-smokers. | |||||
| 8-OHdG, 8-hydroxy-2′deoxyguanosine(μg/g creatinine); NO, nitrogen oxides (μmol/l); 1-OHPG, 1-hydroxypyrene-glucuronide(μmol/mol creatinine). | |||||
| 8-OHdG | |||||
| Smokers | 5 | 10.2 (4.6) | 8 | 10.5 (8.2) | 0.94 |
| Non-smokers | 42 | 13.6 (7.3) | 16 | 7.3 (4.8) | 0.0004 |
| Subtotal | 47 | 13.3 (7.1) | 24 | 8.4 (6.2) | 0.004 |
| p value† | 0.19 | 0.34 | |||
| NO | |||||
| Smokers | 4 | 58.7 (19.5) | 8 | 40.1 (10.0) | 0.15 |
| Non-smokers | 35 | 48.0 (23.8) | 16 | 37.6 (14.1) | 0.06 |
| Subtotal | 39 | 49.1 (23.4) | 24 | 38.4 (12.7) | 0.03 |
| p value† | 0.365 | 0.63 | |||
| 1-OHPG | |||||
| Smokers | 5 | 0.16 (0.10) | 8 | 0.18 (0.07) | 0.69 |
| Non-smokers | 42 | 0.12 (0.07) | 16 | 0.07 (0.04) | 0.01 |
| Subtotal | 47 | 0.12 (0.08) | 24 | 0.11 (0.07) | 0.63 |
| p value† | 0.35 | 0.003 | |||