Table 1

 Summary characteristics of talc exposed populations in talc producing companies

StudyCohort definitionTalc exposureOtherSmoking
Selevan et al, talc miners4All male talc miners radiographed in annual surveys of workers in dusty trade in Vermont (US), from five companies with at least one year employment between 1940 and 1969, followed up from 1940–75No information Levels >20 mppcf not uncommonRadon (up to 1.2 WL  =  240 pCi/l), possibly tremoliteNo information
Selevan et al, talc millers4All male talc millers radiographed in annual surveys of workers in dusty trade in Vermont (US), from five companies with at least one year employment between 1940 and 1969, followed up from 1940–75No information Levels >20 mppcf not uncommonNone, quartz <0.25%No information
Wergeland et al, talc miners15All male employees from a Norwegian mine with at least one year employment between 1944 and 1972 followed up from 1953–87In 1980: 0.94–97.35 mg/m3 peak at 319 mg/m3 0.2–0.9 f/ml3.5 pCi/l radon76% smokers in 1981
Wergeland et al, talc millers15All male employees from a Norwegian talc mill with at least two years employment between 1935 and 1972 followed up from 1953–87In 1980: 1.4–54.1 mg/m3 peak at 109 mg/m3 0.2–0.9 f/mlNoneNo information
Wild et al, French talc millers21All male employees from a French talc mill (site A) with at least one year employment between 1945 and 1994 followed up from 1968–95>30 mg/m3 in production until the 1970s, 5–30 mg/m3 until 1990, <5 mg/m3 since except some dusty jobsNone, quartz <3%. Some workers had past quartz exposure in former jobs59% present smokers in 1989; 39% in a French population survey in 1986
Wild et al, Austrian talc millers and miners21All male workers of an Austrian talc producing company having been employed at least one year in three mines (site B to D) and mills or in the head office (site E) between 1972 and 1995 followed up from 1972–95.>30 mg/m3 in sites B and C before 1960 and for millers in D 1970–80, 5–30 for millers 1960–80, <5 since 1980Quartz (and no talc) in site D and in miners of site B until 1960 Elsewhere quartz <3%42% smokers in 1988; 16% ex-smokers in site B
Coggiola et al, Italian talc miners22All male employees from Italian talc mine with at least one year employment between 1946 and 1995 followed up from 1946–95Decreased from more than 200 mppcf in 1950 to less than 5 mppcf in 1965 (Rubino 1979)High quartz in the past. Radon in 1992, 500 Bq/m3 =  13.5 pCi/l47% smokers in 1993; 34% in an adult Italian population survey in 1994
Coggiola et al, Italian talc millers22All male employees from Italian talc mill with at least one year employment between 1946 and 1995 followed up from 1946–95Decreased from about 20 mppcf until 1960 to about 5 mppcf in 1975 (Rubino 1979). In 1993 1.3 mg/m3 (personal communication)None Quartz <1%44% smokers in 1993; 34% in an adult Italian population survey in 1994