Relative risk of mortality from lung cancer and non-malignant respiratory disease by levels of cumulative respirable crystalline silica exposure in UK industrial silica sand workers
| Cumulative RCS exposure | n | RR* | (95% CI) | RR† | (95% CI) |
|---|---|---|---|---|---|
| (mg/m3-years) | |||||
| *Analysed simultaneously with attained age. | |||||
| †Analysed simultaneously with attained age, period from first employment, employment status, year of starting employment, and quarry. | |||||
| ‡Any part of the death certificate coded to ICD 162 or C33/C34. | |||||
| §Underlying cause of death coded to ICD 460–519 or J00–J99. | |||||
| Lung cancer‡ | |||||
| <0.13 | 20 | 1.0 | 1.0 | ||
| 0.13–<0.40 | 21 | 1.24 | (0.66 to 2.34) | 1.14 | (0.60 to 2.18) |
| 0.40–<1.00 | 22 | 1.42 | (0.76 to 2.67) | 1.12 | (0.58 to 2.18) |
| ⩾1.00 | 19 | 0.88 | (0.45 to 1.73) | 0.92 | (0.44 to 1.92) |
| p value for trend | p = 0.79 | p = 0.80 | |||
| Non-malignant respiratory diseases§ | |||||
| <0.13 | 19 | 1.0 | 1.0 | ||
| 0.13–<0.40 | 19 | 1.24 | (0.67 to 2.28) | 1.33 | (0.71 to 2.50) |
| 0.40–<1.00 | 21 | 1.22 | (0.65 to 2.30) | 0.98 | (0.51 to 1.88) |
| ⩾1.00 | 24 | 1.46 | (0.82 to 2.62) | 1.12 | (0.59 to 2.14) |
| p = 0.48 | p = 0.98 | ||||