Change in lung function and inflammatory parameters in blood during a work shift
| Parameter | No | Before work | After work | Difference | Paired t test p value | |
|---|---|---|---|---|---|---|
| Mean (SD) | Mean (SD) | Mean (SD) | 95% CI | |||
| *Significantly changed from before work shift p<0.05 (Student’s paired t test). | ||||||
| FVC (l) | 28 | 5.34 (0.9) | 5.25 (0.9)* | −0.08 (0.17) | −0.15 to −0.02; | 0.02 |
| FEV1 (l) | 28 | 4.15 (0.7) | 4.07 (0.7)* | −0.08 (0.18) | −0.15 to −0.01 | 0.03 |
| FEF25–75% (l/s) | 28 | 3.81 (1.3) | 3.70 (1.2) | −0.11 (0.48) | −0.30 to 0.07 | 0.2 |
| PEF (l/s) | 28 | 758 (148) | 770 (149) | 12 (78) | −18 to 43 | 0.4 |
| White blood cells (109/l) | 25 | 6.9 (1.2) | 7.7 (1.5)* | 0.8 (1.5) | 0.21 to 1.4 | 0.01 |
| IL-6 (ng/l) | 16 | 1.5 (0.6) | 3.31 (2.7)* | 1.8 (2.4) | 0.51 to 3.1 | <0.01 |
| Fibrinogen (g/l) | 16 | 2.56 (0.4) | 2.55 (0.7) | 0.01 (0.6) | −0.31 to 0.29 | 0.9 |