Descriptive statistical analysis of N-methylformamide (NMF), N-acetyl-S-(N-methylcarbamoyl)cysteine (AMCC) in urine, and N-methylcarbamoylated haemoglobin (NMHb) in blood of workers exposed to N,N-dimethylformamide (DMF)
| Median | Min | Max | 95% | Median | Min | Max | 95% | |
|---|---|---|---|---|---|---|---|---|
| Volume and creatinine related concentrations are given for NMF and AMCC. | ||||||||
| EG, exposure group; S, smoker; NS, non-smoker; Wet, wet spinning; Dry, dry spinning; Min, minimum; Max, maximum; 95%, 95th centile; n, number of workers. | ||||||||
| NMF (mg/l) | NMF (mg/g) | |||||||
| All (n = 34/35) | 10.2 | 1.6 | 59.7 | 48.1 | 9.6 | 2.5 | 72.8 | 33.1 |
| EG 1 (n = 13/14) | 8.0 | 1.6 | 47.7 | 38.4 | 6.5 | 2.5 | 26.9 | 26.8 |
| EG 2 (n = 14) | 18.6 | 4.7 | 49.0 | 47.4 | 11.3 | 3.1 | 33.5 | 33.1 |
| EG 3 (n = 7) | 27.6 | 1.8 | 59.7 | 54.1 | 12.5 | 5.1 | 72.8 | 58.5 |
| S (n = 17/18) | 9.7 | 1.6 | 45.0 | 34.8 | 9.1 | 2.5 | 29.8 | 27.5 |
| NS (n = 16) | 16.1 | 1.6 | 59.7 | 51.7 | 13.1 | 3.2 | 72.8 | 43.3 |
| Wet (n = 10) | 8.4 | 1.8 | 45.0 | 38.1 | 10.6 | 2.5 | 29.8 | 28.5 |
| Dry (n = 14) | 13.3 | 1.6 | 59.7 | 52.7 | 7.8 | 3.1 | 72.8 | 46.9 |
| AMCC (mg/l) | AMCC (mg/g) | |||||||
| All (n = 34/35) | 11.3 | 0.6 | 116.5 | 64.4 | 8.5 | 1.3 | 56.2 | 37.5 |
| EG 1 (n = 13/14) | 6.2 | 1.5 | 38.6 | 22.6 | 6.4 | 1.3 | 14.9 | 11.3 |
| EG 2 (n = 14) | 17.7 | 4.4 | 83.7 | 64.4 | 14.6 | 3.2 | 56.2 | 39.4 |
| EG 3 (n = 7) | 29.1 | 0.6 | 116.5 | 91.9 | 14.7 | 4.0 | 50.6 | 41.6 |
| S (n = 17/18) | 12.6 | 2.2 | 116.5 | 66.5 | 13.3 | 3.8 | 50.6 | 34.4 |
| NS (n = 16) | 9.4 | 0.6 | 83.7 | 46.9 | 7.2 | 1.3 | 56.2 | 29.4 |
| Wet (n = 10) | 17.5 | 0.6 | 116.5 | 83.2 | 17.6 | 3.8 | 50.6 | 40.5 |
| Dry (n = 14) | 11.7 | 2.2 | 83.7 | 64.4 | 8.1 | 4.6 | 56.2 | 39.4 |
| NMHb (nmol/g globin) | ||||||||
| All (n = 34/35) | 121.2 | 21.3 | 464.9 | 221.1 | ||||
| EG 1 (n = 13/14) | 55.1 | 21.3 | 169.6 | 156.1 | ||||
| EG 2 (n = 14) | 122.8 | 53.0 | 464.9 | 297.1 | ||||
| EG 3 (n = 7) | 152.6 | 133.3 | 254.5 | 239.9 | ||||
| S (n = 17/18) | 129.7 | 22.1 | 464.9 | 244.6 | ||||
| NS (n = 16) | 117.7 | 21.3 | 254.5 | 218.7 | ||||
| Wet (n = 10) | 110.8 | 26.7 | 464.9 | 348.3 | ||||
| Dry (n = 14) | 129.7 | 41.8 | 254.5 | 223.5 | ||||