Cause specific standardised mortality ratios for the workers exposed to TCDD, higher chlorinated dioxins, and phenoxy herbicides, in the producers and sprayers cohorts
| Cause of death (ICD9) | Production workers | Sprayers | ||||
|---|---|---|---|---|---|---|
| n = 813 | n = 699 | |||||
| person-years = 17613.18 | person-years = 20043.53 | |||||
| Obs/exp | SMR | (95% CI) | Obs/exp | SMR | (95% CI) | |
| All causes | 122/123.5 | 0.99 | (0.82 to 1.18) | 91/148.2 | 0.61 | (0.49 to 0.75) |
| All malignant neoplasms (140–208) | 43/34.6 | 1.24 | (0.90 to 1.67) | 35/42.9 | 0.82 | (0.57 to 1.14) |
| Lip, oral cavity, and pharynx (140–159) | 2/0.7 | 2.75 | (0.33 to 9.94) | 1/1.0 | 1.02 | (0.03 to 5.67) |
| Parts of mouth (141–145) | 2/0.4 | 5.40 | (0.65 to 19.5) | 0/0.5 | 0.00 | (0.00 to 7.52) |
| Nasopharynx (147) | 0/0.1 | 0.00 | (0.00 to 41.8) | 1/0.1 | 8.33 | (0.21 to 46.3) |
| Digestive organs and peritoneum (150–159) | 15/10.8 | 1.38 | (0.77 to 2.28) | 16/13.9 | 1.15 | (0.66 to 1.87) |
| Oesophagus (150) | 2/1.0 | 1.94 | (0.24 to 7.02) | 1/1.4 | 0.72 | (0.02 to 3.99) |
| Stomach (151) | 2/1.8 | 1.10 | (0.13 to 3.97) | 3/2.2 | 1.36 | (0.28 to 3.98) |
| Colon (153) | 2/3.2 | 0.62 | (0.08 to 2.25) | 8/4.1 | 1.94 | (0.84 to 3.83) |
| Rectum, rectosigmoid junction, and anus (154) | 5/2.0 | 2.45 | (0.79 to 5.73) | 4/2.7 | 1.47 | (0.40 to 3.76) |
| Liver and intrahepatic bile ducts (155) | 1/0.6 | 1.58 | (0.04 to 8.78) | 0/0.9 | 0.00 | (0.00 to 4.17) |
| Pancreas (157) | 3/1.4 | 2.09 | (0.43 to 6.10) | 0/1.8 | 0.00 | (0.00 to 2.08) |
| Respiratory and intrathoracic organs (160–165) | 13/9.3 | 1.39 | (0.74 to 2.38) | 6/12.0 | 0.50 | (0.18 to 1.09) |
| Trachea, bronchus, and lung (162) | 12/8.8 | 1.37 | (0.71 to 2.39) | 5/11.1 | 0.45 | (0.15 to 1.05) |
| Other sites within respiratory system (163–165) | 1/0.3 | 3.86 | (0.10 to 21.5) | 1/0.4 | 2.47 | (0.06 to 13.7) |
| Bone, connective tissue, skin, and breast (170–175) | 2/2.6 | 0.78 | (0.09 to 2.80) | 2/2.4 | 0.85 | (0.10 to 3.06) |
| Connective and other soft tissue (171) | 0/0.2 | 0.00 | (0.00 to 19.3) | 1/0.2 | 4.28 | (0.11 to 23.8) |
| Malignant melanoma of skin (172) | 0/1.2 | 0.00 | (0.00 to 3.00) | 1/1.6 | 0.61 | (0.02 to 3.41) |
| Female breast (174) | 1/0.8 | 1.29 | (0.03 to 7.16) | 0/0.0 | 0.00 | (0.00 to 214) |
| Male breast (175) | 1/0.03 | 31.53 | (0.80 to 175) | 0/0.0 | 0.00 | (0.00 to 86.0) |
| Genitourinary organs (179–189) | 2/4.9 | 0.41 | (0.05 to 1.47) | 5/5.7 | 0.88 | (0.29 to 2.06) |
| Prostate (185) | 1/2.7 | 0.37 | (0.01 to 2.08) | 2/3.3 | 0.60 | (0.07 to 2.16) |
| Kidney and other unspecified urinary organs (189) | 1/0.8 | 1.19 | (0.03 to 6.63) | 3/1.1 | 2.73 | (0.56 to 7.98) |
| Other and unspecified sites (190–199) | 4/3.2 | 1.25 | (0.34 to 3.19) | 3/4.2 | 0.72 | (0.15 to 2.11) |
| Brain (191) | 1/1.2 | 0.82 | (0.02 to 4.56) | 1/1.6 | 0.62 | (0.02 to 3.43) |
| Other and ill defined sites (195) | 1/0.1 | 17.79 | (0.45 to 98.8) | 0/0.1 | 0.00 | (0.00 to 55.0) |
| Without specification of site (199) | 2/1.7 | 1.21 | (0.15 to 4.36) | 2/2.1 | 0.93 | (0.11 to 3.37) |
| Lymphatic and haemopoietic tissue (200–208) | 5/3.03 | 1.65 | (0.53 to 3.85) | 2/3.8 | 0.52 | (0.06 to 1.89) |
| Hodgkin’s disease (201) | 1/0.2 | 5.58 | (0.14 to 31.0) | 0/0.2 | 0.00 | (0.00 to 16.1) |
| Non-Hodgkin lymphoma (200,202) | 1/1.1 | 0.87 | (0.02 to 4.87) | 1/1.5 | 0.69 | (0.02 to 3.84) |
| Multiple myeloma and immunoproliferative neoplasms (203) | 3/0.5 | 5.51 | (1.14 to 16.1) | 0/0.7 | 0.00 | (0.00 to 5.29) |
| Myeloid leukaemia (205) | 0/0.7 | 0.00 | (0.00 to 5.29) | 1/0.9 | 1.16 | (0.03 to 6.44) |
| Benign and unspecified neoplasms (210–239) | 0/0.3 | 0.00 | (0.00 to 11.0) | 1/0.4 | 2.45 | (0.06 to 13.6) |
| Endocrine and metabolic disorders, immunity disorders (240–259, 270–279) | 4/3.4 | 1.16 | (0.32 to 2.97) | 3/4.4 | 0.69 | (0.14 to 2.01) |
| Diseases of blood and blood forming organs (280–289) | 0/0.2 | 0.00 | (0.00 to 16.3) | 1/0.3 | 3.83 | (0.10 to 21.3) |
| Diseases of nervous system (320–359) | 1/1.8 | 0.55 | (0.01 to 3.08) | 1/2.1 | 0.47 | (0.01 to 2.64) |
| Diseases of circulatory system (390–459) | 51/53.0 | 0.96 | (0.72 to 1.27) | 33/63.4 | 0.52 | (0.36 to 0.73) |
| Rheumatic fever and rheumatic heart disease (390–398) | 1/0.8 | 1.33 | (0.03 to 7.38) | 1/0.8 | 1.18 | (0.03 to 6.56) |
| Hypertensive disease (401–405) | 0/1.1 | 0.00 | (0.00 to 3.49) | 1/1.2 | 0.81 | (0.02 to 4.50) |
| Ischaemic heart disease (410–414) | 38/36.4 | 1.04 | (0.74 to 1.43) | 22/44.5 | 0.49 | (0.31 to 0.75) |
| Disorders of pulmonary circulatory and other heart disease (415–429) | 0/3.8 | 0.00 | (0.00 to 0.97) | 4/4.7 | 0.85 | (0.23 to 2.17) |
| Cerebrovascular disease (430–438) | 8/8.2 | 0.98 | (0.42 to 1.92) | 5/8.9 | 0.56 | (0.18 to 1.31) |
| Other diseases of circulatory system (440–459) | 4/2.8 | 1.44 | (0.39 to 3.69) | 0/3.2 | 0.00 | (0.00 to 1.16) |
| Diseases of the respiratory system (480–519) | 9/9.7 | 0.93 | (0.42 to 1.76) | 6/10.8 | 0.55 | (0.20 to 1.21) |
| Pneumonia (480–486) | 1/2.0 | 0.51 | (0.01 to 2.83) | 0/2.0 | 0.00 | (0.00 to 1.82) |
| Bronchitis, chronic and unspecified, emphysema, and asthma (490–493) | 4/3.3 | 1.20 | (0.33 to 3.07) | 0/3.5 | 0.00 | (0.00 to 1.04) |
| Remainder diseases of respiratory system (640–478, 494–519) | 4/4.3 | 0.93 | (0.25 to 2.38) | 6/5.2 | 1.16 | (0.43 to 2.54) |
| Diseases of digestive system (520–599) | 7/4.2 | 1.68 | (0.67 to 3.45) | 3/5.0 | 0.60 | (0.12 to 1.74) |
| Other parts digestive system (530–579) | 4/3.1 | 1.31 | (0.36 to 3.34) | 3/3.8 | 0.80 | (0.16 to 2.34) |
| Urinary system (580–599) | 3/1.1 | 2.72 | (0.56 to 7.95) | 0/1.3 | 0.00 | (0.00 to 2.91) |
| Reproduction related causes (600–676) | 1/0.1 | 6.96 | (0.18 to 38.7) | 0/0.1 | 0.00 | (0.00 to 30.3) |
| Diseases of musculoskeletal system and connective tissue (710–739) | 0/0.4 | 0.00 | (0.00 to 8.56) | 1/0.5 | 2.13 | (0.05 to 11.8) |
| External causes (e800–999) | 6/13.1 | 0.46 | (0.17 to 1.00) | 7/15.5 | 0.45 | (0.18 to 0.93) |