Potential risk factors | Main outcomes | |||||
---|---|---|---|---|---|---|
First follow up | Second follow up | |||||
At least 1 respiratory symptom (n = 20) | At least 1 respiratory symptom (n = 15) | Increase in BR* (n = 23) | ||||
n (%) | OR (95% CI) | n (%) | OR (95% CI) | n (%) | OR (95% CI) | |
*3.2-fold decrease in PC20. | ||||||
†Current versus non- and ex-smokers. | ||||||
‡Physician diagnosed asthma as reported by subject. | ||||||
§Symptoms of non-welding related asthma. | ||||||
Baseline | ||||||
Smoking† | ||||||
Yes | 12/109 (11.0) | 1.62 (0.64–4.14) | 7/96 (7.3) | 0.97 (0.34–2.79) | 10/89 (11.2) | 0.90 (0.37–2.15) |
No | 8/113 (7.1) | 8/107 (7.5) | 13/105 (12.4) | |||
Atopy | ||||||
Yes | 12/107 (11.2) | 1.69 (0.66–4.31) | 5/96 (5.2) | 0.53 (0.18–1.62) | 15/93 (16.1) | 2.24 (0.90–5.55) |
No | 8/115 (7.0) | 10/107 (9.3) | 8/101 (7.9) | |||
Asthma‡ | ||||||
Yes | 2/39 (5.1) | 0.49 (0.11–2.22) | 3/34 (8.8) | 1.25 (0.33–4.69) | 5/34 (14.7) | 1.34 (0.46–3.90) |
No | 18/182 (9.9) | 12/167 (7.2) | 18/158 (11.4) | |||
Symptoms of asthma§ | ||||||
Yes | 5/41 (12.2) | 1.54 (0.52–4.50) | 3/33 (9.1) | 1.32 (0.35–4.95) | 6/34 (17.6) | 1.80 (0.65–4.97) |
No | 15/181 (8.3) | 12/170 (7.1) | 17/160 (10.6) | |||
1st follow up | ||||||
Possible MFF | ||||||
Yes | 8/54 (14.8) | 2.44 (0.92–6.41) | 6/46 (13.0) | 2.55 (0.84–7.78) | 5/43 (11.6) | 1.11 (0.38–3.24) |
No | 11/165 (3.7) | 8/144 (5.6) | 15/141 (10.6) | |||
Sensitisation | ||||||
Yes | 1/5 (20.0) | 2.54 (0.27–23.89) | 1/4 (25.0) | 2.96 (0.29–30.00) | ||
No | 19/212 (9.0) | 14/184 (7.6) | 18/178 (10.1) | |||
2nd follow up | ||||||
Possible MFF | ||||||
Yes | 12/50 (24.0) | 15.58 (4.19–57.99) | 8/49 (16.3) | 1.65 (0.65–4.18) | ||
No | 3/151 (2.0) | 15/142 (10.6) | ||||
Sensitisation | ||||||
Yes | 1/27 (3.7) | 0.43 (0.05–3.40) | 4/26 (15.4) | 1.40 (0.44–4.49) | ||
No | 14/170 (8.2) | 19/165 (11.5) |