Comparison of neurological symptoms and signs suggestive of peripheral neuropathy for chlorpyrifos (CPF) and referent subjects at baseline (CPF n = 53; referent n = 60) and one-year evaluations (CPF n = 53; referent n = 58)
| Neurological evaluation | Baseline | No. | p value* | One year | No. | p value* |
|---|---|---|---|---|---|---|
| *Fisher’s exact two tailed test. | ||||||
| Symptoms of neuropathy | CPF | 1 | >0.99 | CPF | 0 | |
| Referent | 1 | Referent | 0 | |||
| Signs of neuropathy | ||||||
| Motor signs | ||||||
| Symmetrical weakness | CPF | 0 | CPF | 0 | ||
| Referent | 0 | Referent | 0 | |||
| Sensory signs | ||||||
| Any symmetrical sensory signs | CPF | 3 | >0.99 | CPF | 0 | 0.06 |
| Referent | 4 | Referent | 5 | |||
| Specific abnormalities | ||||||
| Pin-pain | CPF | 0 | CPF | 0 | ||
| Referent | 0 | Referent | 0 | |||
| Vibration | CPF | 2 | >0.99 | CPF | 0 | 0.06 |
| Referent | 3 | Referent | 5 | |||
| Joint position | CPF | 0 | CPF | 0 | ||
| Referent | 0 | Referent | 0 | |||
| Fine touch | CPF | 0 | CPF | 0 | ||
| Referent | 0 | Referent | 0 | |||
| Touch pressure | CPF | 1 | >0.99 | CPF | 0 | >0.99 |
| Referent | 1 | Referent | 1 | |||
| Abnormal ankle reflexes | ||||||
| Decreased or absent | CPF | 2 | 0.68 | CPF | 2 | 0.44 |
| Referent | 4 | Referent | 5 | |||