Table 2

Studies of PAH environmentally exposed subjects with DNA adduct measurements

Author, yearCountryType of air PAHs sampledPAH monitoringPAH analysis techniqueSmoking statusDNA adduct analysisSeason of sampling
*Carcinogenic PAHs: include benzo(a)anthracene, benzo(b)fluoranthene, benzo(k)fluoranthene, chrysene, benzo(a)pyrene, dibenzo(ah)anthracene, indeno(1,2,3-cd)pyrene, benzo(ghi)perylene.
B(a)P, benzo(a)pyrene; HPLC, high performance liquid chromatography; GC/MS, gas chromatography/mass spectrometry.
NS, non-smokers; All, smokers and non-smokers.
n.a., information not available.
Perera, 1992PolandB(a)PStationaryGC/MSAll32P-postlabelling; ELISAWinter + summer
Grzybowska,1993Polandn.a.All32P-postlabelling (nuclease P1)Winter + summer
Hemminki, 1994Swedenn.a.NS32P-postlabelling (nuclease P1)Winter
Binkova, 1995Czech RepublicCarcinogenic PAHsPersonalHPLCNS32P-postlabelling (Nuclease P1 & Butanol extraction)Winter
Farmer, 1996EuropeParticulate matterStationaryn.a.NS32P-postlabelling with HPLCn.a.
Binkova, 1996Czech RepublicCarcinogenic PAHs*; B(a)PPersonalHPLCNS32P-postlabelling (butanol extraction)Winter
Nielsen, 1996DenmarkB(a)PStationaryn.a.NS32P-postlabelling (nuclease P1 and butanol extraction)Winter
Yang, 1996Italyn.a.n.a.32P-postlabelling (nuclease P1)Winter
Lewtas, 1997Czech RepublicCarcinogenic PAHs*PersonalHPLCAll32P-postlabelling (butanol extraction)n.a.
Whyatt, 1998PolandPM10Stationaryn.a.AllELISAWinter
Poirier, 1998Germany, KuwaitB(a)PStationaryGCn.a.32P-postlabelling (nuclease P1); DelfiaWinter + summer
Peluso, 1998ItalyB(a)PPersonalHPLCNS32P-postlabelling (nuclease P1)Winter + summer
Autrup, 1999DenmarkB(a)PStationaryn.a.NS32P-postlabelling (butanol extraction)Winter
Marafie, 2000Kuwait, UKB(a)PStationaryn.a.NS32P-postlabelling (nuclease P1 and butanol extraction)Winter + summer
Palli, 2000Italyn.a.All32P-postlabelling (nuclease P1)Winter + summer
Georgiadis, 2001GreeceCarcinogenic PAHs*Personaln.a.NS32P-postlabelling (nuclease P1)Winter + summer
Ruchiwarat, 2002ThailandCarcinogenic PAHs*PersonalHPLCNS32P-postlabelling (butanol extraction)Winter