Histopathological scores of 37 nasal mucosa specimens from 20 exposed workers.
| No. | Age (y) | Smoking (1) | ExpoV (μg/m3) (2) | ExpoT (3) | Bx no. (4) | Epithel (5) | Ulcer (6) | Atypia (7) | Basal (8) | Oedema (9) | Fibro (10) | Ves (11) | Int. (12) | Infl. inf. (13) | Lymph (14) | Plas (15) | Eos (16) | Neut (17) | Glands (18) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| (1) S, smoker; NS, non-smoker. | |||||||||||||||||||
| (2) Exposure level. | |||||||||||||||||||
| (3) Exposure duration in years. | |||||||||||||||||||
| (4) Biopsy number: A = anterior septum mucosa, B = middle turbinate. | |||||||||||||||||||
| (5) Epithelium: 1 = pseudostratified cylindric ciliated epithelium, 2 = immature squamous epithelium, 3 = mature squamous epithelium. | |||||||||||||||||||
| (6) Ulceration: 0 = absent, 1 = present. | |||||||||||||||||||
| (7) Atypia: 0 = absent, 1 = squamous atypia, 2 = mild dysplasia. | |||||||||||||||||||
| (8) Basalm = thickness of basal membrane from 0 to 3. | |||||||||||||||||||
| (9) Oedema: varying from 0 to 4. | |||||||||||||||||||
| (10) Fibrosis: varying from 0 to 4. | |||||||||||||||||||
| (11) Vessels: vasocongestion varying from 0 to 4. | |||||||||||||||||||
| (12) Intima: hypercellularity of endothelial cells varying from 0 to 4. | |||||||||||||||||||
| (13) Intensity of global inflammatory infiltrate varying from 0 to 4. | |||||||||||||||||||
| (14) Intensity of lymphohistiocytic infiltrate varying from 0 to 4. | |||||||||||||||||||
| (15) Intensity of plasmocytic infiltrate varying from 0 to 4. | |||||||||||||||||||
| (16) Intensity of eosinophilic infiltrate varying from 0 to 4. | |||||||||||||||||||
| (17) Intensity of neutrophilic infiltrate varying from 0 to 4. | |||||||||||||||||||
| (18) Glands: 0 = normal, 1 = dilatation, 2 = metaplasia, 3 = dilatation and metaplasia, 4 = hyperplasia, 5 = calcification. | |||||||||||||||||||
| 1 | 39 | S | 580.2 | 13 y 11 m | 2788A | 3 | 0 | 0 | 0 | 3 | 2 | 3 | 1 | 2 | 1 | 1 | 1 | 2 | 1 |
| 2788B | – | – | – | – | – | – | – | – | – | – | – | – | – | – | |||||
| 2 | 23 | NS | 580.2 | 1 y 6 m | 2789A | 3 | 0 | 1 | 2 | 1 | 3 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 |
| – | – | – | – | – | – | – | – | – | – | – | – | – | – | ||||||
| 3 | 42 | NS | 338.9 | 2 y 8 m | 3271A | 2 | 1 | 0 | 2 | 3 | 0 | 3 | 0 | 3 | 3 | 3 | 2 | 2 | 0 |
| 3271B | 1 | 0 | 0 | 0 | 3 | 0 | 2 | 0 | 2 | 1 | 2 | 1 | 2 | 0 | |||||
| 4 | 22 | S | 580.2 | 2 y 6 m | 3272A | 2 | 1 | 2 | 0 | 2 | 1 | 2 | 0 | 2 | 1 | 2 | 1 | 1 | 1 |
| 3272B | 1 | 0 | 0 | 0 | 3 | 0 | 4 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | |||||
| 5 | 27 | NS | 580.2 | 5 y 9 m | 3432A | 2 | 1 | 1 | 0 | 2 | 1 | 2 | 0 | 3 | 2 | 3 | 2 | 1 | 0 |
| 3432B | 2 | 1 | 0 | 0 | 2 | 1 | 2 | 0 | 2 | 2 | 2 | 1 | 1 | 0 | |||||
| 6 | 42 | S | 580.2 | 5 y | 3433A | 2 | 0 | 0 | 0 | 2 | 1 | 2 | 0 | 2 | 2 | 1 | 2 | 1 | 0 |
| 3433B | 2 | 0 | 0 | 0 | 2 | 0 | 2 | 0 | 3 | 3 | 3 | 1 | 1 | 0 | |||||
| 7 | 42 | NS | 580.2 | 3 y 9 m | 3434A | 2 | 0 | 1 | 0 | 2 | 1 | 1 | 0 | 3 | 2 | 2 | 1 | 3 | 0 |
| 3434B | 1 | 0 | 0 | 0 | 2 | 1 | 1 | 0 | 2 | 2 | 1 | 1 | 2 | 0 | |||||
| 8 | 43 | S | 580.2 | 6 y | 0235A | 3 | 1 | 1 | 0 | 2 | 0 | 1 | 0 | 3 | 3 | 3 | 2 | 2 | 2 |
| 0235B | 2 | 0 | 1 | 0 | 3 | 1 | 4 | 0 | 2 | 2 | 1 | 0 | 1 | 2 | |||||
| 9 | 40 | NS | 2133.6 | 2 y 2 m | 0633A | 2 | 0 | 2 | 0 | 2 | 1 | 3 | 0 | 3 | 2 | 2 | 1 | 2 | 0 |
| 0633B | 3 | 0 | 0 | 0 | 2 | 1 | 1 | 0 | 2 | 2 | 2 | 2 | 1 | 0 | |||||
| 10 | 29 | NS | 580.2 | 7 y 9 m | 0801A | 3 | 1 | 1 | 0 | 2 | 0 | 1 | 0 | 2 | 2 | 2 | 1 | 2 | 0 |
| 0801B | 2 | 0 | 0 | 0 | 3 | 0 | 3 | 0 | 2 | 3 | 2 | 1 | 0 | 0 | |||||
| 11 | 27 | NS | 580.2 | 14 y 4 m | 0802A | 2 | 0 | 0 | – | – | – | – | – | – | – | – | – | – | 0 |
| 0802B | 2 | 0 | 0 | 1 | 1 | 0 | 3 | 0 | 3 | 3 | 3 | 1 | 1 | 0 | |||||
| 12 | 57 | S | 580.2 | 7 y 8 m | 0909A | 3 | 0 | 0 | 0 | 2 | 2 | 2 | 0 | 2 | 2 | 2 | 1 | 1 | 0 |
| 0909B | 2 | 0 | 2 | 1 | 3 | 1 | 3 | 0 | 2 | 2 | 2 | 2 | 3 | 0 | |||||
| 13 | 39 | NS | 580.2 | 15 y | 0910A | 2 | 1 | 1 | 0 | 2 | 1 | 2 | 0 | 2 | 2 | 1 | 1 | 0 | 1 |
| 0910B | 1 | 0 | 0 | 0 | 3 | 0 | 3 | 0 | 2 | 1 | 2 | 2 | 1 | 0 | |||||
| 14 | 31 | NS | 580.2 | 13 y | 0911A | 2 | 1 | 0 | 1 | 2 | 1 | 2 | 0 | 3 | 2 | 3 | 1 | 1 | 0 |
| 0911B | – | – | – | – | – | – | – | – | – | – | – | – | – | – | |||||
| 15 | 29 | NS | 580.2 | 2 y 10 m | 0959A | 2 | 1 | 0 | 1 | 2 | 2 | 2 | 0 | 4 | 3 | 2 | 1 | 2 | 2 |
| 0959B | 1 | 0 | 0 | 1 | 2 | 2 | 1 | 0 | 2 | 2 | 1 | 1 | 1 | 0 | |||||
| 16 | 39 | S | 338.9 | 7 y 1 m | 0960A | 2 | 0 | 1 | 1 | 2 | 2 | 3 | 0 | 3 | 3 | 2 | 2 | 3 | 3 |
| 0960B | 2 | 0 | 1 | 0 | 2 | 2 | 3 | 1 | 3 | 2 | 2 | 1 | 1 | 0 | |||||
| 17 | 21 | NS | 2133.6 | 1 y 4 m | 0961A | 2 | 1 | 1 | 0 | 2 | 2 | 2 | 0 | 3 | 3 | 2 | 3 | 1 | 1 |
| 0961B | 1 | 0 | 0 | 1 | 3 | 2 | 2 | 0 | 2 | 1 | 1 | 2 | 2 | 0 | |||||
| 18 | 39 | S | 34.7 | 3 y 2 m | 1104A | 3 | 1 | 0 | 0 | 2 | 4 | 0 | 0 | 2 | 2 | 2 | 1 | 1 | 2 |
| 1104B | 3 | 1 | 0 | 1 | 3 | 2 | 3 | 0 | 3 | 3 | 2 | 2 | 1 | 4 | |||||
| 19 | 30 | S | 60.45 | 7 y 9 m | 1105A | 1 | 0 | 0 | 2 | 1 | 2 | 1 | 0 | 2 | 2 | 2 | 1 | 1 | 0 |
| 1105B | 2 | 0 | 0 | 1 | 2 | 1 | 2 | 0 | 2 | 2 | 2 | 2 | 2 | 0 | |||||
| 20 | 34 | S | 60.45 | 6 y | 1106A | 3 | 0 | 0 | 0 | 3 | 2 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 2 |
| 1106B | 1 | 0 | 0 | 0 | 2 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | |||||