Association of organochlorine compounds (ng/ml) in cord serum and TSH levels at birth
| Crude association* | ||||
|---|---|---|---|---|
| TSH <10 mU/l (n=60) | TSH ⩾10 mU/l (n=10) | Gestational age adjusted odds ratio of having TSH ⩾10 mU/l OR (95% CI) n=70 | ||
| *Student’s t test on base 2 log transformed variables. | ||||
| †Sum of the individual congeners 28, 52, 101, 118, 138, 153, and 180. | ||||
| ‡p=0.03. | ||||
| Median | Geometric mean (range) | Geometric mean (range) | Doubling the dose | |
| HCB | 1.14 | 1.14 (0.96–1.35) | 1.14 (0.71–1.84) | 1.15 (0.48 to 2.76) |
| p,p′DDE | 0.85 | 0.81 (0.64–1.02) | 1.20 (0.60–2.39) | 1.60 (0.87 to 2.92) |
| β-HCH | 0.54 | 0.23 (0.14–0.37) | 0.86 (0.52–1.40)‡ | 1.81 (1.06 to 3.11)‡ |
| ∑PCBs† | 0.27 | 0.34 (0.28–0.42) | 0.44 (0.23–0.82) | 1.38 (0.75 to 2.57) |
| % Quantifiable | % Quantifiable | Quantifiable v non-quantifiable | ||
| PCB 138 | 25.0% | 40.0% | 2.54 (0.58 to 11.18) | |
| PCB 180 | 23.33% | 20.0% | 0.97 (0.17 to 5.47) | |
| PCB 153 | 21.67% | 20.0% | 0.90 (0.16 to 5.04) | |
| % Detectable | % Detectable | Detectable v non-detectable | ||
| PCB 118 | 45.0% | 70.0% | 2.76 (0.62 to 12.31) | |