Correlations (Spearman) between inflammatory cells and mediators in nasal lavage fluid and exposure to microbial agents
| Spearman rank correlation coefficient | ||||||||
|---|---|---|---|---|---|---|---|---|
| Wednesday exposure | Median exposure | |||||||
| Inflammatory markers | Fungal spores | β(1→3) glucans | Bacteria | Endotoxins | Fungal spores | β(1→3) glucans | Bacteria | Endotoxins |
| *p<0.1, **p<0.05, ***p<0.01. | ||||||||
| Thursday level of: | ||||||||
| Neutrophils (%) | 0.55*** | −0.09 | −0.20 | 0.03 | 0.54*** | 0.04 | −0.12 | −0.21 |
| IL-8 (pg/ml) | −0.21 | 0.17 | 0.17 | 0.17 | −0.08 | 0.47*** | 0.10 | 0.07 |
| ECP (ng/ml) | 0.04 | −0.15 | 0.03 | 0.19 | 0.16 | 0.09 | 0.07 | 0.05 |
| MPO (ng/ml) | −0.26 | 0.08 | 0.23 | 0.53*** | −0.11 | 0.09 | 0.12 | 0.30 |
| Change from Monday to Thursday | ||||||||
| Neutrophils (%) | 0.33* | 0.12 | 0.09 | −0.15 | 0.10 | 0.17 | 0.01 | −0.42** |
| Free IL8 (pg/ml) | −0.05 | 0.11 | −0.18 | −0.10 | −0.04 | 0.33* | −0.07 | −0.13 |
| ECP (ng/ml) | 0.30 | −0.20 | 0.07 | 0.05 | 0.14 | 0.05 | 0.18 | −0.08 |
| MPO (ng/ml) | 0.04 | −0.13 | −0.01 | 0.31* | −0.10 | −0.16 | −0.06 | −0.07 |