Adjusted (for age and smoking habit) odds ratios (OR) for renal cell cancer in relation to occupational risk factors as adjusted for age and smoking habits, and stratified for glutathione S-transferases M1-1 and T1-1 (GSTM1 and GSTT1)
| Genotype combinations | Cases* | Controls* | OR (95% CI) | p for interaction |
|---|---|---|---|---|
| Non-exposed subjects bearing either GSTM1 null or GSTT1 null were used as reference. | ||||
| *Twelve cases and 20 controls with double exposure. | ||||
| Not exposed | ||||
| Either GSTM1 null or GSTT1 null | 24 | 75 | 1.00 (reference) | |
| GSTM1 present and GSTT1 present | 19 | 54 | 1.08 (0.53 to 2.18) | |
| Exposed to solvents | ||||
| Either GSTM1 null or GSTT1 null | 15 | 18 | 2.65 (1.15 to 6.10) | |
| GSTM1 present and GSTT1 present | 11 | 10 | 2.91 (1.06 to 7.99) | 0.152 |
| Exposed to metals | ||||
| Either GSTM1 null or GSTT1 null | 10 | 28 | 1.08 (0.45 to 2.60) | |
| GSTM1 present and GSTT1 present | 9 | 8 | 2.97 (1.00 to 8.89) | 0.456 |
| Exposed to pesticides | ||||
| Either GSTM1 null or GSTT1 null | 13 | 24 | 1.21 (0.38 to 3.85) | |
| GSTM1 present and GSTT1 present | 13 | 6 | 6.64 (1.81 to 24.45) | 0.016 |