Odds ratios (OR) for renal cell cancer in relation to occupational risk factors as adjusted for age and smoking habits, and stratified for glutathione S-transferase M1-1 (GSTM1)
| Genotypes | Cases* | Controls* | OR (95% CI) | p for interaction |
|---|---|---|---|---|
| Subjects with GSTM1 null and none of the exposures under study were used as reference. | ||||
| *Twelve cases and 20 controls with double exposure. | ||||
| No exposure | ||||
| GSTM1 null | 21 | 63 | 1.00 (reference) | |
| GSTM1 present | 22 | 66 | 0.98 (0.48 to 1.96) | |
| Exposure to solvents | ||||
| GSTM1 null | 15 | 15 | 3.06 (1.26 to 7.43) | |
| GSTM1 present | 11 | 13 | 2.23 (0.82 to 6.12) | 0.572 |
| Exposure to metals | ||||
| GSTM1 null | 10 | 27 | 1.14 (0.46 to 2.82) | |
| GSTM1 present | 9 | 9 | 2.73 (0.91 to 8.22) | 0.093 |
| Exposure to pesticides | ||||
| GSTM1 null | 11 | 19 | 1.59 (0.48 to 5.34) | |
| GSTM1 present | 15 | 11 | 3.46 (1.12 to 10.74) | 0.445 |