Ascorbic and uric acid concentrations in nasal lavage fluid by exposure and group
| Exposure | Ascorbic acid concentration (μmol/l) | Uric acid concentration (μmol/l) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | Pre | Post | Mean difference | (95% CI) | p value | n | Pre | Post | Mean difference | (95% CI) | p value | |
| Asthma | ||||||||||||
| Air | 9 | 0.29 | 0.52 | 0.24 | (−0.05 to 0.52) | 0.14 | 12 | 8.19 | 8.51 | 0.32 | (−1.07 to 1.72) | 0.66 |
| Sulphur dioxide 200ppb | 8 | 0.36 | 0.46 | 0.1 | (−0.16 to 0.36) | 0.46 | 11 | 7.82 | 8.68 | 0.87 | (−1.28 to 3.02) | 0.45 |
| Sulphuric acid 200 μg/m3 | 9 | 0.26 | 0.45 | 0.20 | (−0.06 to 0.45) | 0.17 | 12 | 7.80 | 9.23 | 1.43 | (−0.69 to 3.54) | 0.21 |
| Sulphuric acid 2000 μg/m3 | 10 | 0.25 | 0.38 | 0.13 | (−0.37 to 0.32) | 0.90 | 12 | 8.20 | 9.90 | 1.70 | (0.13 to 3.28) | 0.06 |
| Ammonium bisulphate 200 μg/m3 | 9 | 0.35 | 0.44 | 0.09 | (−0.27 to 0.44) | 0.64 | 12 | 8.46 | 9.51 | 1.05 | (−1.07 to 3.18) | 0.35 |
| Ammonium bisulphate 2000 μg/m3 | 9 | 0.23 | 0.34 | 0.11 | (−0.09 to 0.30) | 0.32 | 11 | 8.09 | 10.32 | 2.23 | (0.11 to 4.34) | 0.07 |
| Normal | ||||||||||||
| Air | 12 | 0.52 | 0.61 | 0.10 | (−0.24 to 0.44) | 0.58 | 12 | 7.71 | 9.70 | 1.99 | (0.51 to 3.47) | 0.02 |
| Sulphur dioxide 200ppb | 12 | 0.48 | 0.81 | 0.33 | (−0.06 to 0.60) | 0.14 | 12 | 8.28 | 9.44 | 1.16 | (−1.12 to 3.44) | 0.34 |
| Sulphuric acid 200 μg/m3 | 11 | 0.65 | 0.56 | -0.09 | (−0.46 to 0.28) | 0.65 | 11 | 7.90 | 10.52 | 2.62 | (1.57 to 3.66) | 0.001 |
| Sulphuric acid 2000 μg/m3 | 10 | 0.99 | 0.92 | -0.07 | (−0.54 to 0.40) | 0.78 | 12 | 8.62 | 10.88 | 2.26 | (0.79 to 3.73) | 0.02 |
| Ammonium bisulphate 200 μg/m3 | 12 | 0.55 | 0.66 | 0.11 | (−0.16 to 0.43) | 0.40 | 12 | 8.88 | 11.16 | 2.27 | (0.59 to 3.96) | 0.02 |
| Ammonium bisulphate 2000 μg/m3 | 11 | 0.54 | 1.08 | 0.54 | (0.02 to 1.03) | 0.06 | 11 | 7.98 | 10.81 | 2.82 | (0.89 to 4.76) | 0.02 |