Table 2

Observed and expected deaths by cause and SMR for all PVC cohort members

Cause of death (ICD9)ObservedExpectedSMR (95% CI)
*Significant at 5% level.
†Other gastrointestinal sites including oesophagus, small intestine, and pancreas.
All causes (1–999)144185.90.78 (0.65 to 0.91)*
All cancers (140–209)5743.71.30 (0.99 to 1.69)
Cancer of lip, oral cavity, and pharynx (140–149)46.60.60 (0.16 to 1.55)
Cancer of digestive system (150–159)3724.11.54 (1.08 to 2.12)*
    Malignant neoplasm of stomach (151)63.31.83 (0.67 to 3.99)
    Malignant neoplasm of colon and rectum (153, 154)32.8
    Malignant neoplasm of liver (155)2514.11.78 (1.15 to 2.62)*
    Malignant neoplasm of other GI sites† (150, 152, 157)32.9
Cancer of respiratory system (160–165)46.70.59 (0.16 to 1.52)
Cancer of genitourinary system (179–189)21.2
Malignant neoplasm of brain (191)20.7
Cancer of lymphatic and haematopoietic tissue (200–208)72.62.71 (1.09 to 5.60)*
    Lymphoid leukaemia (204)20.2
Diabetes mellitus (250)34.9
Diseases of the circulatory system (390–459)1235.00.34 (0.18 to 0.60)*
    Ischaemic heart disease (410–414)46.00.66 (0.18 to 1.69)
    Cerebrovascular disease (430–438)417.60.23 (0.06 to 0.58)*
Diseases of the digestive system (520–579)1223.30.52 (0.26 to 0.90)*
    Diseases of liver and biliary tract (570–579)1121.40.51 (0.26 to 0.92)*
    Chronic liver disease and cirrhosis (571)716.40.42 (0.17 to 0.88)*
Diseases of the genitourinary system (580–589)33.2
Unknown (797–799)66.10.98 (0.36 to 2.13)
Injury and poisoning (800–999)3648.80.74 (0.52 to 1.02)