Table 5

Association between hepatic biochemical function measurements^5-151 and continuous air concentrations of styrene for pooled data from study 1 and study 2

Hepatic biochemical marker^‡		Partial regression coefficients
Hepatic biochemical marker^‡		Air styrene	Age	Sex	BMI	Alcohol	R²
AST (IU/ml)	0.22^5-165	0.46^5-150	10.27^5-160	−0.19	0.23	0.27
ALT (IU/ml)	0.52^5-165	1.32^5-150	15.15^5-160	0.34	0.39	0.27
GGT (IU/ml)	0.05	1.26^5-165	14.75^5-160	−0.02	1.08	0.34
AP (IU/ml)	0.12	0.30	9.44	−0.08	0.35	0.12
Direct bilirubin (mg/dl)	0.0007^5-150	−0.0005	0.03	−0.003	0.003	0.18
Direct/total bilirubin ratio	0.0005	0.001	0.09^5-160	−0.007^5-150	0.007^5-150	0.26

↵5-150 p<0.05;
↵5-160 p<0.01;
↵5-165 p<0.001.
↵5-151 From multiple linear regression models regressing hepatic biochemical function measurement on continuous air concentrations of styrene (ppm), age (y), sex (male), body mass index, and alcohol consumption (g/week).
ALT=alanine aminotransferase; AST=aspartate aminotransferase; AP=alkaline phosphatase; GGT=γ-glutamyl transferase.