Adjusted differences in hepatic biochemical function measurements4-151 by air and blood concentration of styrene (pooled data from study 1 and study 2)
| Hepatic biochemical marker | Air styrene (ppm) | Blood styrene (mg/l) | |||||
|---|---|---|---|---|---|---|---|
| <25 | >25 | <0.275 | >0.275 | ||||
| AST (IU/ml) | 2.34-152 | 4.9 | 3.5 | 2.4 | |||
| ALT (IU/ml) | 4.1 | 8.14-150 | 5.6 | 5.6 | |||
| GGT (IU/ml) | 3.9 | 4.9 | 4.6 | 2.5 | |||
| AP (IU/ml) | 4.2 | 10.34-150 | 5.6 | 10.74-150 | |||
| Direct bilirubin (mg/dl) | 0.054-160 | 0.084-160 | 0.064-160 | 0.084-160 | |||
| Direct/total bilirubin ratio | 0.194-165 | 0.194-165 | 0.194-165 | 0.184-165 | |||
↵4-150 p<0.05;
↵4-160 p<0.01;
↵4-165 p<0.001.
↵4-151 From multiple linear regression models regressing hepatic biochemical function measurement on air and blood concentrations of styrene, respectively, with covariates: age, sex, body mass index, and alcohol consumption (g/week).
↵4-152 Difference in hepatic biochemical marker measurement in exposed group compared with unexposed referent group. All differences are in positive direction, representing values greater than the referent group.
ALT=alanine aminotransferase; AST=aspartate aminotransferase; AP=alkaline phosphatase; GGT=γ-glutamyl transferase.