Table 6

Regression coefficients and risk estimates of dying for lung cancer by smoking, airflow obstruction, cumulative exposure to radon daughters and silica (continuous variables) and by ILO radiological categories of silicosis (categorical variable) based on the Cox's multiple regression analysis of 665 silicotics with available spirometry (34 lung cancer deaths)

Variables β6-150 SE p Value RR6-151 95% CI
Smoking (cigarettes/day)0.04680.02020.0208RR per 10 cigarettes/day1.601.07 to 2.37
Airflow obstruction (FEV1/VC−predicted)×1000.04910.01250.0001RR per 20% below predicted2.671.63 to 4.36
Radon daughters exposure (WLM)0.00370.00140.0112RR per 100 WLM1.451.10 to 1.90
Cumulative exposure to respirable SiO2(gh/m3)6-152 0.00260.04120.9491RR per 10 gh/m3 1.030.46 to 2.30
Severity of radiological silicosis0.02590.22810.9093
(ILO category)6-152 6-153 RR for category 1/0–1/21.00
RR for category 2/1–2/31.030.66 to 1.61
RR for category 3/2+1.050.43 to 2.57
  • 6-150 β=regression coefficient.

  • 6-151 RR=relative risk.

  • 6-152 Variables that did not enter the stepwise model.

  • 6-153 Categorical variable included as 0, 1, 2.