NES tests4-150 | One way ANOVA4-1514-152 p value adjusted results4-160 | Current exposure (n=27) | Former exposure (n=90) | Controls (n=64) | Dose-effect relation4-164 | ||||||||||||||||||||||||||
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Duration of exposure | Cumulative exposure | Interaction | |||||||||||||||||||||||||||||
Unadjusted results4-160 | Adjusted results4-160 | Unadjusted results4-160 | Adjusted results4-160 | Unadjusted results4-160 | Adjusted results4-160 | β | p Value | β | p Value | β | p Value | ||||||||||||||||||||
Symbol-digit substitution4-153 (s/digit) | 0.01 | 2.6 (1.2,4-151 2.1–3.6) | 1.0 (1.2,4-151 0.8–1.5) | 2.5 (1.2,4-1511.7–4.9) | 0.9 (1.1, 0.8–1.2) | 2.4 (1.2, 2.0–4.0) | 0.9 (1.1, 0.8–1.2) | 0.21 | <0.01 | 0.15 | 0.05 | 0.18 | 0.02 | ||||||||||||||||||
Hand-eye coordination4-154 (root mean squared error) | <0.01 | 1.8 (0.3, 1.3 to 2.7) | −0.0 (0.3, −0.56 to 0.73) | 1.9 (0.3,4-152 1.3 to 2.7) | −0.1 (0.2, −0.4 to 0.8) | 1.7 (0.2, 1.3 to 2.6) | −0.1 (0.2, −0.4 to 0.8) | 0.18 | >0.10 | 0.14 | >0.10 | 0.17 | 0.06 | ||||||||||||||||||
Digit span forwards4-154(mean number) | <0.01 | 5.4 (0.9,4-152 3.7 to 7.0) | −0.33 (0.9,4-151 −2.26 to 1.07) | 5.6 (0.9,4-152 3.9 to 8.0) | 0.3 (0.9, −1.8 to 2.0) | 6.2 (1.0, 4.0 to 7.9) | 0.3 (0.9, −1.8 to 2.0) | −0.16 | 0.08 | −0.17 | 0.08 | −0.16 | 0.09 | ||||||||||||||||||
Simple reaction time4-153(ms) | >0.10 | 204 (1.2, 151 to 324) | 1.1 (1.2, 0.8 to 1.6) | 197 (1.2, 118 to 381) | 1.0 (1.2, 0.7 to 1.4) | 192 (1.6, 132 to 292) | 1.0 (1.2, 0.7 to 1.4) | 0.08 | >0.10 | 0.05 | >0.10 | 0.05 | >0.10 | ||||||||||||||||||
Colour-word vigilance4-154(ms) | >0.01 | 553 (67, 444 to 666) | −1.9 (65.6, −122 to 08) | 558 (62.4, 445 to 749) | −3.5 (66.7, −98 to 140) | 558 (74, 449 to 742) | −3.5 (66.7, −98 to 140) | 0.21 | 0.03 | 0.18 | 0.07 | 0.21 | 0.03 | ||||||||||||||||||
Associate learning4-154(number correct) | >0.10 | 6.4 (2.3, 3 to 9) | −0.1 (2.2, −4.0 to 3.3) | 6.3 (2.1, 2 to 9) | 0.1 (2.0, −5.1 to 3.5) | 6.9 (2.1, 2 to 9) | 0.1 (2.0, −5.1 to 3.5) | −0.18 | 0.05 | −0.18 | 0.05 | −0.17 | 0.06 | ||||||||||||||||||
Associate recall (%)4-154 | >0.10 | 102.4 (31.4, 40 to 200) | 9.0 (29.1, −45 to 103) | 89.8 (25.3, 17 to 150) | −1.3 (27.5, −77 to 90) | 90.8 (27.9, 20 to 180) | −1.3 (27.5, −77 to 90) | 0.04 | >0.10 | 0.02 | >0.10 | 0.02 | >0.10 |
↵4-150 Neurobehavioural examination system. For details, see subjects and methods.
↵4-151 p<0.05 v controls,
↵4-152 p<0.05 v other two groups, ANOVA one way Duncan's multiple range test.
↵4-153 Log normal distribution: geometric mean (geometric SD, range).
↵4-154 Mean (SD, range).
↵4-160 Unadjusted results are raw data; adjusted results are the raw data adjusted for age, schooling, years of welding, and alcohol use.
↵4-164 Multiple linear regression analysis. Regression coefficients (β) and p values for the predictor variables, duration of exposure, cumulative exposure, and the interaction term duration×concentration of exposure are presented.
Overall mean concentration of exposure: not significant predictor (β<0.14, p>0.17).