Reference
|
Data source
|
Exposure metric
|
Statistical model
|
Risk estimate
|
Collins and Marty19
| Geometric mean of risk estimates from rat inhalation studies24-26
| Respirable silica (quartz) particles | Linearised multistage (GLOBAL 86) | 2.9 × 10−4 (95% upper confidence limit) (with surface area correction factor) |
Goldsmith et al
18
| Mortality study of diatomaceous earth workers4
| Cumulative exposure to respirable silica (exposure intensity × years) (mainly cristobalite) with 15 year lag | Linearised multistage (GLOBAL 86) | 1.83 × 10−7 |
Cohort mortality study of South African gold miners21
| Gold mining dust containing quartz | Linearised multistage (GLOBAL 86) | 6.75 × 10−5 |
Goldsmith et al
18
| Risk estimates from rat inhalation studies24-26
| Respirable silica (quartz) particles | Linearised multistage (GLOBAL 86) | 6 × 10−3 (95% upper confidence limit) (highest of 5 estimates) (with surface area correction factor) |
Riceet al (this study) | Mortality study of diatomaceous earth workers2
| Cumulative exposure to respirable silica with 10 year lag (mainly cristobalite) in mg/m3.years | Poisson regression: linear relative rate | 3.8 × 10−4 (white men) |