Table 4

Adjusted4-150 OR (95% CI) between oesophageal cancer and exposure to selected occupational substances, by histological subtypes, Montreal, 1979–85

SubstancesExposure levelAll histological subtypes (n=99)Squamous cell carcinoma (n=63)
nexpOR95% CInexpOR95% CI
Dusts:
 Carbon blackAny112.11.0 to 4.3103.41.5 to 7.7
Non-substantial91.80.8 to 4.082.91.2 to 7.2
Substantial25.70.9 to 36.028.91.2 to 64.3
 Chrysotile asbestosAny211.40.8 to 2.4172.01.1 to 3.8
Non-substantial191.40.8 to 2.5162.11.1 to 4.0
Substantial21.30.3 to 6.211.10.1 to 9.7
 AluminaAny171.30.7 to 2.3141.80.9 to 3.5
Non-substantial141.20.6 to 2.3111.50.7 to 3.2
Substantial31.60.4 to 6.233.50.9 to 13.9
 Abrasive dustAny221.00.6 to 1.6171.30.7 to 2.3
Non-substantial141.20.6 to 2.3101.50.7 to 3.2
Substantial80.70.3 to 1.571.00.4 to 2.5
 CelluloseAny101.50.7 to 3.140.90.3 to 2.6
Non-substantial81.70.7 to 4.021.00.3 to 3.7
Substantial20.90.2 to 4.620.60.1 to 4.9
 Wood dustAny190.80.4 to 1.3161.00.5 to 1.9
 Crystalline silicaAny180.70.4 to 1.3130.80.4 to 1.7
Liquids and vapours:
 Mineral spiritsAny171.10.6 to 2.0161.91.0 to 3.7
Non-substantial81.60.7 to 3.772.61.0 to 6.6
Substantial90.90.4 to 1.991.60.7 to 3.6
 TolueneAny161.20.7 to 2.2152.01.0 to 3.9
Non-substantial91.00.5 to 2.291.80.8 to 4.1
Substantial71.50.6 to 3.762.40.9 to 6.4
 Synthetic adhesivesAny191.30.8 to 2.3161.81.0 to 3.4
Non-substantial101.40.7 to 3.082.00.9 to 4.7
Substantial91.20.6 to 2.681.60.7 to 3.8
 Other paints and varnishes4-151 Any181.50.8 to 2.6162.31.2 to 4.4
Non-substantial122.01.0 to 4.1102.81.2 to 6.3
Substantial61.00.4 to 2.461.80.7 to 4.7
 Sulphuric acidAny152.21.2 to 4.3102.81.2 to 6.1
Non-substantial122.01.0 to 4.092.21.2 to 6.3
Substantial34.11.0 to 17.213.10.3 to 28.1
 SolventsAny391.10.7 to 1.7301.40.8 to 2.5
Non-substantial161.00.5 to 1.9121.30.6 to 2.6
Substantial231.10.6 to 1.9181.60.8 to 3.0
 Lube oils and greasesAny250.70.4 to 1.2180.90.5 to 1.6
Gases and fumes:
 Metal oxide fumesAny171.10.6 to 2.0131.50.8 to 3.0
Non-substantial101.50.8 to 2.971.80.8 to 4.1
Substantial70.60.2 to 1.861.10.4 to 3.4
 Nitrogen oxidesAny210.90.6 to 1.6161.20.7 to 2.4
 Gasoline engine emissionsAny410.90.6 to 1.5240.90.5 to 1.5
 Carbon monoxideAny450.70.4 to 1.1250.60.3 to 1.0
Metals:
 Aluminium compoundsAny191.10.6 to 1.9161.60.8 to 3.0
Non-substantial151.10.6 to 2.1121.50.7 to 3.0
Substantial41.10.4 to 3.242.20.7 to 6.8
 Iron compoundsAny251.00.6 to 1.7211.70.9 to 3.0
Non-substantial151.40.7 to 2.6132.31.2 to 4.8
Substantial100.80.4 to 1.581.10.5 to 2.6
 Lead compoundsAny410.70.4 to 1.1250.70.4 to 1.3
 Chromium VI compoundsAny60.60.2 to 1.461.00.4 to 2.6
 Metallic dustAny271.00.6 to 1.7201.30.7 to 2.3
Non-substantial171.30.7 to 2.3131.70.8 to 3.3
Substantial100.80.4 to 1.670.90.4 to 2.2
 Mild steel dustAny181.10.6 to 2.0151.70.9 to 3.2
Non-substantial111.30.7 to 2.7102.21.0 to 4.8
Substantial70.90.4 to 2.051.10.4 to 3.1
Aromatic hydrocarbons:
 PAHs from any sourceAny640.90.5 to 1.5400.90.5 to 1.7
 Benzo(a)pyreneAny241.10.7 to 1.9181.60.8 to 3.0
Non-substantial191.00.5 to 1.7161.60.8 to 3.0
Substantial52.30.8 to 6.521.70.4 to 8.2
 PAHs from coalAny101.20.6 to 2.550.90.3 to 2.5
Non-substantial40.70.2 to 2.120.50.1 to 2.4
Substantial62.00.8 to 5.331.70.5 to 6.2
 PAHs from petroleumAny641.00.6 to 1.6411.00.6 to 1.9
 PAHs from other sourcesAny160.70.4 to 1.2110.70.4 to 1.5
 Mononuclear aromatic hydrocarbonsAny290.80.5 to 1.3231.20.7 to 2.0
Other:
 Aliphatic aldehydesAny211.30.8 to 2.4131.20.6 to 2.5
Non-substantial181.40.7 to 2.5101.10.5 to 2.3
Substantial31.30.3 to 4.632.30.6 to 9.6
 FormaldehydeAny130.90.5 to 1.8101.20.5 to 2.5
 Alkanes (C5 to C17)Any330.90.6 to 1.5251.30.7 to 2.3
Non-substantial151.20.7 to 2.2141.50.7 to 3.1
Substantial180.70.4 to 1.3111.10.5 to 2.3
 Alkanes (C18+)Any290.80.5 to 1.2211.00.6 to 1.8
 Cleaning agentsAny171.00.6 to 1.8100.80.4 to 1.8
  • 4-150 Adjusted for age, respondent status, birthplace, educational level, beer consumption, spirits consumption, β-carotene index, cigarette-years, smoking patterns.

  • 4-151 This group comprises paints used on surfaces other than metal and varnishes used on surfaces other than wood.

  • PAHs=polycyclic aromatic hydrocarbons; nexp=number of exposed cases.