Table 5

Populations (n), population aetiological fractions (PEFs), aetiological fractions among exposed (EEFs), (95%CIs)

Agent		Population aetiological fraction (PEF)				Aetiological fraction among exposed (EEF)
Agent		n	Proportion exposed			MRR	95% CI	PEF	95% CI	n	MRR	95% CI	EEF	95% CI
Aliphatic and alicyclic hydrocarbon solvents	2	0.094	1.3	0.8 to 2.0	0.022	0.00 to 0.047		2	1.3	0.8 to 2.0	0.23	0.00 to 0.50
Chlorinated hydrocarbon solvents and related compounds	3	0.061	1.2	0.7 to 1.9	0.010	0.00 to 0.029		20	1.4	1.0 to 1.8	0.29	0.00 to 0.44
Chromium and chromium compounds	3	0.034	1.1	0.7 to 1.6	0.003	0.00 to 0.013		9	1.4	0.9 to 2.3	0.29	0.00 to 0.57
Fungicides	1	0.0034	1.4	0.3 to 7.2	0.001	0.00 to 0.0029		2	1.3	0.4 to 3.8	0.23	0.00 to 0.74
Insecticides								3	1.5	0.6 to 3.7	0.33	0.00 to 0.73
Iron and iron compounds	1	0.067	1.3	0.7 to 2.5	0.016	0.00 to 0.040		1	1.3	0.7 to 2.5	0.23	0.00 to 0.60
Lead and lead compounds	2	0.11	1.1	0.8 to 1.6	0.010	0.00 to 0.041		4	1.1	0.8 to 1.5	0.09	0.00 to 0.33
Nickel and nickel compounds	2	0.063	2.0	1.2 to 3.2	0.032	0.011 to 0.043		4	1.9	1.2 to 3.2	0.47	0.17 to 0.69
Polycyclic aromatic hydrocarbons (PAHs)	2	0.029	1.4	0.8 to 2.3	0.008	0.00 to 0.016		4	1.5	0.9 to 2.4	0.33	0.00 to 0.58
Silica dust	2	0.063	1.5	0.8 to 2.7	0.021	0.00 to 0.040		3	1.4	0.9 to 2.0	0.29	0.00 to 0.50
Wood dust	4	0.062	1.2	0.9 to 1.6	0.01	0.00 to 0.023		5	1.2	0.9 to 1.6	0.17	0.00 to 0.38

Only agents with both MRRs >1.0 considered. Negative lower confidence bounds of PEFs and EEFs forced to zero.
MRR=meta risk ratio, as estimated from population based and hospital based case-control studies for PFF, and all but proportional studies for EEF.