RT Journal Article
SR Electronic
T1 0309  Burden of cancer attributable to occupational diesel engine exhaust exposure in Canada0309  Burden of cancer attributable to occupational diesel engine exhaust exposure in Canada
JF Occupational and Environmental Medicine
JO Occup Environ Med
FD BMJ Publishing Group Ltd
SP A37
OP A37
DO 10.1136/oemed-2014-102362.115
VO 71
IS Suppl 1
A1 Joanne Kim
A1 Cheryl E Peters
A1 Chris McLeod
A1 Sally Hutchings
A1 Lesley Rushton
A1 Manisha Pahwa
A1 Paul A Demers
YR 2014
UL http://oem.bmj.com/content/71/Suppl_1/A37.2.abstract
AB Objectives To estimate the number of new lung cancers cases in Canada attributable to occupational diesel engine exhaust (DEE), which IARC classified as a definite human carcinogen in 2012. This is part of a larger effort to estimate the current burden of occupational cancers in Canada. Method Relative risks were selected from two recent studies of miners and truckers with quantitative exposure-response. CAREX Canada estimates of exposure prevalence and level by detailed industry and occupation were supplemented by a literature search for DEE measurement data. For each exposure group, RRs were assigned based upon the estimated mean exposure. Employment trends of industries and occupations were based upon census data from multiple years. Annual Labour Force Survey data were used to attribute age- and tenure-distribution, as well as short-term turnover characteristics. Survival was adjusted to age at entry into the exposed cohort during the risk exposure period 1961–2001. The attributable fraction (AF) for DEE-related lung cancers will be calculated by province, sex, industry and occupation. Results Approximately 1.4 million workers were exposed to DEE during the risk exposure period. The initial estimated AFs for DEE-related lung cancers are: 4.92% for males, 0.29% for females, and 2.70% overall. Conclusions These burden estimates are somewhat higher than recent estimates from other groups (1.3–1.8%). They account for the most recent evidence for the risk of lung cancer from occupational DEE exposure, as well as detailed historical exposure assessment and labour force trends. Sensitivity analyses are underway to determine the influential assumptions.